Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong; Institute of Microelectronics, Agency for Science, Technology and Research (A * STAR), Singapore.
State Key Lab of Advanced Welding and Joining, Harbin Institute of Technology, China.
Mater Sci Eng C Mater Biol Appl. 2012 Aug 1;32(6):1469-79. doi: 10.1016/j.msec.2012.04.027. Epub 2012 Apr 24.
(Ti, O)/Ti, (Ti, N)/Ti and (Ti, O, N)/Ti composite coatings were fabricated on NiTi shape memory alloy via plasma immersion ion implantation and deposition (PIIID). Surface morphology of samples was investigated using atomic force microscopy (AFM) and scanning electron microscopy (SEM). Cross-sectional morphology indicated that the PIIID-formed coatings were dense and uniform. X-ray diffraction (XRD) was used to characterize the phase composition of samples. X-ray photoelectron spectroscopy (XPS) results showed that the surface of coated NiTi SMA samples was Ni-free. Nanoindentation measurements and pin-on-disc tests were carried out to evaluate mechanical properties and wear resistance of coated NiTi SMA, respectively. For the in vitro biological assessment of the composite coatings in terms of cell morphology and cell viability, osteoblast-like SaOS-2 cells and breast cancer MCF-7 cells were cultured on NiTi SMA samples, respectively. SaOS-2 cells attached and spread better on coated NiTi SMA. Viability of MCF-7 cells showed that the PIIID-formed composite coatings were noncytotoxic and coated samples were more biocompatible than uncoated samples.
(Ti, O)/Ti、(Ti, N)/Ti 和 (Ti, O, N)/Ti 复合涂层通过等离子体浸没离子注入和沉积（PIIID）在 NiTi 形状记忆合金上制备。使用原子力显微镜（AFM）和扫描电子显微镜（SEM）研究样品的表面形貌。横截面形貌表明，PIIID 形成的涂层致密且均匀。X 射线衍射（XRD）用于表征样品的相组成。X 射线光电子能谱（XPS）结果表明，涂覆 NiTi SMA 样品的表面不含镍。纳米压痕测量和销盘试验分别用于评估涂覆 NiTi SMA 的力学性能和耐磨性。为了从细胞形态和细胞活力方面对复合涂层进行体外生物评估，成骨样 SaOS-2 细胞和乳腺癌 MCF-7 细胞分别在 NiTi SMA 样品上培养。SaOS-2 细胞在涂覆的 NiTi SMA 上附着和铺展得更好。MCF-7 细胞的活力表明，PIIID 形成的复合涂层无细胞毒性，涂覆样品比未涂覆样品更具生物相容性。
