肾盂高级别神经内分泌癌伴局灶鳞状化生并与肾结石相关：一例报告

High-grade Neuroendocrine Carcinoma With Focal Squamous Metaplasia of Renal Pelvis Associated With Renal Calculus: Study of a Case.

作者信息

Huang Yan-Ping, Chen Bin, Sun Xiang-Zhou, Guo Yan, Yang Shi-Cong, Deng Chun-Hua, Huang Yi-Ran

机构信息

Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Andrology, Shanghai, People's Republic of China.

Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.

出版信息

Urol Case Rep. 2014 May 16;2(3):93-6. doi: 10.1016/j.eucr.2013.12.004. eCollection 2014 May.

DOI:10.1016/j.eucr.2013.12.004

PMID:26952913

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4733027/

Abstract

Mixed neuroendocrine and non-neuroendocrine type of tumor in renal pelvis is rare and presents a high-grade malignancy. We present a case report that a 57-year-old man had no history of small cell cancer but presented a high-grade neuroendocrine carcinoma with focal squamous metaplasia and multiple stones simultaneously in the right renal pelvis. The patient underwent nephroureterocystectomy 9 months before this presentation, with evidence of multiple metastatic tumors in various parts of the body. The case of mixed neuroendocrine tumor with stones in the renal pelvis carries a poor prognosis and poses a therapeutic challenge to urologists.

摘要

肾盂混合性神经内分泌和非神经内分泌肿瘤罕见，具有高度恶性。我们报告一例病例，一名57岁男性既往无小细胞癌病史，但在右肾盂同时出现了伴有局灶性鳞状化生的高级别神经内分泌癌及多发结石。该患者在此次就诊前9个月接受了肾输尿管膀胱切除术，有身体各部位多发转移瘤的证据。肾盂混合性神经内分泌肿瘤合并结石的病例预后较差，给泌尿外科医生带来了治疗挑战。