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心流倾向的个体差异与一种多巴胺D2受体基因变体有关。

Individual differences in flow proneness are linked to a dopamine D2 receptor gene variant.

作者信息

Gyurkovics Mate, Kotyuk Eszter, Katonai Eniko Rozsa, Horvath Erzsebet Zsofia, Vereczkei Andrea, Szekely Anna

机构信息

Doctoral School of Psychology, Eötvös Loránd University, Izabella u. 46, H-1064 Budapest, Hungary; Institute of Psychology, Eötvös Loránd University, Izabella u. 46, H-1064 Budapest, Hungary.

Institute of Psychology, Eötvös Loránd University, Izabella u. 46, H-1064 Budapest, Hungary; Postdoctoral Research Program, Hungarian Academy of Sciences, Széchenyi István tér 9, H-1051 Budapest, Hungary.

出版信息

Conscious Cogn. 2016 May;42:1-8. doi: 10.1016/j.concog.2016.02.014. Epub 2016 Mar 5.

DOI:10.1016/j.concog.2016.02.014
PMID:26954487
Abstract

Flow is a special mental state characterized by deep concentration that occurs during the performance of optimally challenging tasks. In prior studies, proneness to experience flow has been found to be moderately heritable. In the present study, we investigated whether individual differences in flow proneness are related to a polymorphism of the dopamine D2 receptor coding gene (DRD2 C957T rs6277). This polymorphism affects striatal D2 receptor availability, a factor that has been shown to be related to flow proneness. To our knowledge, this is the first study to investigate the association between this trait and a specific gene variant. In a sample of 236 healthy Hungarian adults, we found that CC homozygotes report higher flow proneness than do T allele carriers, but only during mandatory activities (i.e., studying and working), not during leisure time. We discuss implications of this result, e.g., the potential mediators of the relationship.

摘要

心流是一种特殊的心理状态,其特征是在执行具有最佳挑战性的任务时出现深度专注。在先前的研究中,已发现体验心流的倾向具有中等程度的遗传性。在本研究中,我们调查了心流倾向的个体差异是否与多巴胺D2受体编码基因(DRD2 C957T rs6277)的多态性有关。这种多态性会影响纹状体D2受体的可用性,而这一因素已被证明与心流倾向有关。据我们所知,这是第一项研究该特质与特定基因变体之间关联的研究。在一个由236名匈牙利健康成年人组成的样本中,我们发现CC纯合子在心流倾向上的报告得分高于T等位基因携带者,但仅在强制性活动(即学习和工作)期间如此,在休闲时间则不然。我们讨论了这一结果的影响,例如这种关系的潜在调节因素。

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