Lebedev V S, Veselovskiĭ A V, Fedorov Iu I
Izv Akad Nauk SSSR Biol. 1989 Nov-Dec(6):934-6.
The influence of CuCl2 on inorganic phosphate efflux from resting E. coli and those treated with glucose has been studied. Maintaining of high phosphate gradient on the membrane is possibly only in case of continuous supply of external metabolic energy. Treatment with CuCl2 does not lead to the increase in permeability of the resting cell membrane for phosphates, but it causes the efflux of phosphates in glucose-treated cells. The above data suggest that the efflux is determined by inhibition of energy influx into cell by CuCl2, not by damaging the cytoplasmic membrane.
研究了CuCl₂对静止状态的大肠杆菌以及经葡萄糖处理的大肠杆菌无机磷酸盐外排的影响。只有在持续供应外部代谢能量的情况下，才可能在膜上维持高磷酸盐梯度。用CuCl₂处理不会导致静止细胞膜对磷酸盐的通透性增加，但会导致经葡萄糖处理的细胞中磷酸盐外排。上述数据表明，这种外排是由CuCl₂抑制能量流入细胞所决定的，而不是由破坏细胞质膜所导致的。
