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腰椎环形融合术后相邻节段退变及翻修手术:15年随访结果

Adjacent segment degeneration and revision surgery after circumferential lumbar fusion: outcomes throughout 15 years of follow-up.

作者信息

Maruenda José I, Barrios Carlos, Garibo Felipe, Maruenda Borja

机构信息

Department of Orthopedic Surgery, University Clinic Hospital, Blasco Ibáñez 17, 46010, Valencia, Spain.

Institute for Research on Musculoskeletal Disorders, Valencia Catholic University, Quevedo 2, 46001, Valencia, Spain.

出版信息

Eur Spine J. 2016 May;25(5):1550-1557. doi: 10.1007/s00586-016-4469-5. Epub 2016 Mar 8.

Abstract

PURPOSE

This retrospective study analyzes long-term outcomes (15 years) of circumferential lumbar fusion (CF) for degenerative spine disease using instrumented PLIF. The occurrence of adjacent segment degeneration (ASD) and the reintervention rate was specially focused.

METHODS

A series of 73 patients who underwent CF (1-3 levels) was reviewed. Patients were evaluated preoperatively, at 2, 5, 10 and 15 years after surgery with static and dynamic radiographic studies, CT scan and MRI. Patients completed also the Oswestry-Disability index (ODI), the VAS score, and the patient self-satisfaction questionnaire.

RESULTS

At 2-year follow-up, there was a decrease in the average ODI score (from 72.3 ± 16.4 preop to 30.5 ± 6.2). At 10- and 15-year follow-up, ODI scores return to preoperative scores in patients without revision surgery. The 82.8 % of patients referred an excellentgood self-satisfaction rate at this time. At 5-year follow-up, seven patients (9.6 %) required reoperation because of symptomatic ASD. At 10-year follow-up, reoperated patients increased to 24.6 % (18 cases). Excellent and good self-satisfaction rate decreased to 41.1 % at this time. Radiological ASD was then detected in 37 cases (50.7 %). At 15-year follow-up, nine patients were lost and a total of 24 (37.5 %) required a new surgical treatment because of ASD. The occurrence of revision surgery because of symptomatic ASD was highly dependent of the age of patients at the first surgery and the number of fused levels.

CONCLUSION

Circumferential lumbar fusion provides good clinical results at short-term follow-up. From 2- to 15-year follow-up, outcome worsened significantly. The high rate of ASD occurrence and reintervention questions the reliability of this technique for lumbar fusion.

摘要

目的

本回顾性研究分析了使用器械辅助经椎间孔腰椎椎体间融合术(PLIF)治疗退行性脊柱疾病的环形腰椎融合术(CF)的长期疗效(15年)。特别关注了相邻节段退变(ASD)的发生情况和再次手术率。

方法

回顾了73例行CF(1 - 3个节段)的患者。术前、术后2年、5年、10年和15年对患者进行静态和动态影像学检查、CT扫描及MRI评估。患者还完成了奥斯威斯利功能障碍指数(ODI)、视觉模拟评分(VAS)以及患者自我满意度调查问卷。

结果

在2年随访时,平均ODI评分有所下降(从术前的72.3±16.4降至30.5±6.2)。在10年和15年随访时,未进行翻修手术的患者ODI评分恢复至术前水平。此时82.8%的患者自我满意度为优/良。在5年随访时,7例患者(9.6%)因症状性ASD需要再次手术。在10年随访时,再次手术的患者增至24.6%(18例)。此时优/良自我满意度降至41.1%。随后发现37例(50.7%)存在影像学ASD。在15年随访时,9例患者失访,共有24例(37.5%)因ASD需要再次手术治疗。因症状性ASD进行翻修手术的发生率高度依赖于初次手术时患者的年龄和融合节段数。

结论

环形腰椎融合术在短期随访时提供了良好的临床效果。从2年至15年随访,疗效显著恶化。ASD的高发生率和再次手术率对该腰椎融合技术的可靠性提出了质疑。

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