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基层医疗医生对直接抗病毒治疗时代丙型肝炎管理的看法。

Primary Care Physician Perspectives on Hepatitis C Management in the Era of Direct-Acting Antiviral Therapy.

作者信息

Thomson Mary, Konerman Monica A, Choxi Hetal, Lok Anna S F

机构信息

Department of Internal Medicine, University of Michigan Health System, 2F208 UH, 1500 East Medical Center Drive, Ann Arbor, MI, 48109, USA.

Division of Gastroenterology, Department of Internal Medicine, University of Michigan Health System, 3912 Taubman Center, 1500 East Medical Center Drive, SPC 5362, Ann Arbor, MI, 48109, USA.

出版信息

Dig Dis Sci. 2016 Dec;61(12):3460-3468. doi: 10.1007/s10620-016-4097-2. Epub 2016 Mar 8.

Abstract

BACKGROUND

Primary care physicians (PCPs) play a critical role in the care cascade for patients with chronic hepatitis C (CHC).

AIM

To assess PCP knowledge and perspectives on CHC screening, diagnosis, referral, and treatment.

METHODS

An anonymous survey was distributed to PCPs who participated in routine outpatient care at our hospital.

RESULTS

Eighty (36 %) eligible PCPs completed the survey. More than half were females (60 %) aged 36-50 (55 %) from family (44 %) or internal (49 %) medicine. Overall, PCPs correctly identified high-risk populations for screening, though 19 % failed to identify baby boomers and 45 % failed to identify hemodialysis patients as populations to screen. Approximately half reported they were able to screen at risk patients <50 % of the time secondary to time constraints and difficulty assessing if patients had already been screened. 71 % of PCPs reported they refer all newly diagnosed patients to specialty care. 70 % of PCPs did not feel up to date with current treatment. The majority grossly underestimated efficacy, tolerability and ease of administration, and overestimated treatment duration. Only 9 % felt comfortable treating CHC, even those without cirrhosis. Practice patterns were influenced by specialty and Veterans Affairs Hospital affiliation.

CONCLUSIONS

Although the majority of PCPs are up to date with CHC screening recommendations, few are able to routinely screen in practice. Most PCPs are not up to date with treatment and do not feel comfortable treating CHC. Interventions to overcome screening barriers and expand treatment into primary care settings are needed to maximize access to and use of curative therapies.

摘要

背景

基层医疗医生在慢性丙型肝炎(CHC)患者的治疗过程中发挥着关键作用。

目的

评估基层医疗医生对CHC筛查、诊断、转诊和治疗的知识及观点。

方法

向在我院参与常规门诊治疗的基层医疗医生发放匿名调查问卷。

结果

80名(36%)符合条件的基层医疗医生完成了调查。超过半数为女性(60%),年龄在36 - 50岁之间(55%),来自家庭医学(44%)或内科(49%)。总体而言,基层医疗医生能够正确识别筛查的高危人群,不过19%未能识别婴儿潮一代,45%未能将血液透析患者识别为应筛查人群。约半数报告称,由于时间限制以及难以评估患者是否已接受过筛查,他们仅能在不到50%的时间里对有风险的患者进行筛查。71%的基层医疗医生报告称他们会将所有新诊断的患者转诊至专科护理。70%的基层医疗医生感觉自己对当前治疗方法并不了解。大多数人严重低估了疗效、耐受性和给药便利性,且高估了治疗持续时间。即便对于无肝硬化的患者,也只有9%的人对治疗CHC感到得心应手。实践模式受到专业和退伍军人事务医院附属关系的影响。

结论

尽管大多数基层医疗医生了解CHC筛查建议,但在实践中能够常规进行筛查的人很少。大多数基层医疗医生不了解治疗方法,且对治疗CHC感到不自信。需要采取干预措施来克服筛查障碍,并将治疗扩展到基层医疗环境中,以最大限度地提高获得和使用治愈性疗法的机会。

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