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坦桑尼亚西北部姆万扎市不完全流产患者中的葡萄胎

Hydatidiform moles among patients with incomplete abortion in Mwanza City, North western Tanzania.

作者信息

Kitange Bernard, Matovelo Dismas, Konje Eveline, Massinde Anthony, Rambau Peter

机构信息

Bugando Medical Centre, Obstetrics & Gynecology.

Bugando Medical Centre, Obstetrics & Gynecology; Catholic University of Health & Allied sciences, Obstetrics & Gynecology.

出版信息

Afr Health Sci. 2015 Dec;15(4):1081-6. doi: 10.4314/ahs.v15i4.5.

Abstract

BACKGROUND

Prevalence of hydatidiform mole is not clearly defined, partly because most studies have reported different prevalence rates from different regions. However, there is no previous study that has determined the prevalence and associated risk factors of HM among patients with incomplete abortion evacuated at Bugando Medical Centre (BMC) and Sekou Toure Regional Hospital (STRH).

METHODS

A total of 180 patients with incomplete abortion were enrolled between February 2013 and April 2013. The products of conception were collected and analyzed using Haemotoxylin and Eosin staining technique for hydatidiform moles.

RESULTS

One hundred and eighty patients with incomplete abortion scheduled for uterine evacuation agreed to participate in this study. The overall prevalence of HM was 12.8%. Majority of patients (27.5%) with HM were those aged below 20 years. No significant association was observed with risk factors such as parity, contraceptive use, previous abortion and blood group.

CONCLUSION

The prevalence of HM (12.8%) was high and age between 15-20 years was the only significant associated risk factor with the presence of HM among patients with incomplete abortion. Therefore, we recommend submission of evacuated products of conception for histopathological analysis to minimize missed opportunity.

摘要

背景

葡萄胎的患病率尚无明确定义,部分原因是大多数研究报告的不同地区患病率有所不同。然而,此前尚无研究确定在布甘多医疗中心(BMC)和塞古·杜尔地区医院(STRH)接受清宫术的不全流产患者中葡萄胎的患病率及相关危险因素。

方法

2013年2月至2013年4月期间,共纳入180例不全流产患者。收集妊娠产物并采用苏木精和伊红染色技术分析是否存在葡萄胎。

结果

180例计划进行清宫术的不全流产患者同意参与本研究。葡萄胎的总体患病率为12.8%。大多数葡萄胎患者(27.5%)年龄在20岁以下。未观察到与产次、避孕措施使用、既往流产史和血型等危险因素有显著关联。

结论

葡萄胎的患病率(12.8%)较高,15 - 20岁是不全流产患者中与葡萄胎存在显著相关的唯一危险因素。因此,我们建议对清宫的妊娠产物进行组织病理学分析,以尽量减少漏诊。

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