de Aguiar Guilherme Brasileiro, Pagotto Mário Vítor Caldeira, Conti Mario Luiz Marques, Veiga José Carlos Esteves
Department of Surgery, Division of Neurosurgery, Santa Casa de Sao Paulo School of Medical Sciences, São Paulo, Brazil.
Surg Neurol Int. 2016 Feb 8;7:15. doi: 10.4103/2152-7806.175898. eCollection 2016.
Spontaneous complete thrombosis of a giant aneurysm and its parent artery is a rare event. Their spontaneous recanalization is even rarer, with few reports.
A 17-year-old male patient presenting blurred vision and headache, with a history of seizures, was referred to our service. After further investigation with cranial computed tomography, magnetic resonance imaging (MRI), and cerebral angiography (CAG), it was diagnosed a thrombosed aneurysm of the posterior cerebral artery (PCA) and also complete thrombosis of the PCA. Three years later, he experienced visual worsening. A new MRI scan indicated flow both through the aneurysm and the left PCA, which was further confirmed by CAG. We decided for a noninterventional treatment combined with strict clinical follow-up. The patient continues to present with the previous neurological deficit, without recurrence of headaches.
Thrombosis is not the final event in the natural history of giant aneurysms, and partial thrombosis does not preclude the risk of rupture. Thrombosed aneurysms may display additional growth brought about by wall dissections or intramural hemorrhages. Their treatment may be either surgical or involve endovascular procedures such as embolization. Thrombosed giant aneurysms are dynamic and unstable lesions. A noninterventional treatment is feasible, but aneurysmal growth or recanalization may suggest the need for a more active intervention.
巨大动脉瘤及其供血动脉的自发性完全血栓形成是一种罕见事件。其自发性再通更为罕见,相关报道较少。
一名17岁男性患者因视力模糊和头痛就诊,有癫痫病史。经头颅计算机断层扫描、磁共振成像(MRI)和脑血管造影(CAG)进一步检查后,诊断为大脑后动脉(PCA)血栓形成性动脉瘤,且PCA完全血栓形成。三年后,他视力恶化。新的MRI扫描显示动脉瘤和左PCA均有血流,CAG进一步证实了这一点。我们决定采取非介入治疗并进行严格的临床随访。患者仍有先前的神经功能缺损,未再出现头痛。
血栓形成并非巨大动脉瘤自然病程中的最终事件,部分血栓形成并不能排除破裂风险。血栓形成的动脉瘤可能因壁间剥离或壁内出血而出现额外生长。其治疗方法可以是手术治疗或采用血管内介入手术,如栓塞术。血栓形成的巨大动脉瘤是动态且不稳定的病变。非介入治疗是可行的,但动脉瘤生长或再通可能提示需要更积极的干预措施。