Mao C, Shah A, Hanson D J, Howard J M
Department of Surgery, Mercy Hospital, Toledo, OH, USA.
J Surg Oncol. 1995 May;59(1):67-73. doi: 10.1002/jso.2930590116.
A case of Von Recklinghausen's disease with duodenal somatostatinoma is reported. A search of the world's literature revealed 27 patients with Von Recklinghausen's disease associated with an immunohistologically proved duodenal somatostatinoma. Twenty-nine cases of duodenal somatostatinoma not associated with Von Recklinghausen's disease and 32 cases of pancreatic somatostatinomas have been identified for comparison. While their histology may be similar in many respects, the duodenal and pancreatic somatostatinomas show significant differences, especially in hormonal and growth behaviors. In contrast to its pancreatic counterpart, the duodenal somatostatinoma is frequently associated with Von Recklinghausen's disease, is seldom associated with a recognizable "somatostatin syndrome," often contains psammoma bodies, and is less frequently associated with demonstrable metastases at the time of operation.
报告了1例伴十二指肠生长抑素瘤的冯·雷克林霍增氏病。检索世界文献发现27例冯·雷克林霍增氏病患者伴有经免疫组织学证实的十二指肠生长抑素瘤。另外确定了29例不伴有冯·雷克林霍增氏病的十二指肠生长抑素瘤及32例胰腺生长抑素瘤用于比较。虽然它们的组织学在许多方面可能相似，但十二指肠和胰腺生长抑素瘤存在显著差异，尤其是在激素和生长行为方面。与胰腺生长抑素瘤不同，十二指肠生长抑素瘤常与冯·雷克林霍增氏病相关，很少与可识别的“生长抑素综合征”相关，常含有砂粒体，且手术时发生可证实转移的情况较少。
