Cisło M, Szybejko-Machaj G, Maj J
Przegl Dermatol. 1989 Mar-Apr;76(2):146-51.
PUVA treatment was applied in 16 patients with chronic urticaria (7 with solar urticaria, 2 with cold urticaria and 7 with urticaria of unknown etiology), 26 with chronic disseminated eczema and 41 with atopic dermatitis. In all 9 patients with physical urticaria, a clear-cut improvement was observed. The results from the treatment of chronic urticaria of unknown etiology were considerably poorer (improvement in 2 out of 7 cases). In patients with chronic disseminated eczema, a full remission was present in 5 and considerable improvement in 20 cases. In group of 41 patients with atopic dermatitis, 52 cures were carried out; in 8 patients the cure was repeated 2-3 times at 1,0-0,5-year intervals. Complete recovery was achieved in 34 and significant improvement in 16 out of them. The results presented seem to indicate the effectiveness of PUVA treatment to some allergic skin diseases, the more so that the number of exposures required to obtain a considerable improvement, or even full remission, is comparatively low (3-21 occasions), which reduces the risk of complications.
对16例慢性荨麻疹患者(7例日光性荨麻疹、2例寒冷性荨麻疹和7例病因不明的荨麻疹)、26例慢性播散性湿疹患者和41例特应性皮炎患者进行了补骨脂素加紫外线A(PUVA)治疗。在所有9例物理性荨麻疹患者中,均观察到明显改善。病因不明的慢性荨麻疹的治疗效果相当差(7例中有2例改善)。慢性播散性湿疹患者中,5例完全缓解,20例有显著改善。在41例特应性皮炎患者组中,进行了52次治愈治疗;8例患者在1.0至0.5年的间隔内重复治愈2至3次。其中34例完全康复,16例有显著改善。所呈现的结果似乎表明PUVA治疗对某些过敏性皮肤病有效,而且获得显著改善甚至完全缓解所需的照射次数相对较少(3至21次),这降低了并发症的风险。