Department of Chemistry, Iowa State University, 1605 Gilman Hall, Ames, IA 50011-3111, USA.
Analyst. 2016 Jun 21;141(12):3496-510. doi: 10.1039/c6an00194g. Epub 2016 Mar 11.
In this minireview, we discuss advancements in ion concentration polarization (ICP)-based preconcentration, separation, desalination, and dielectrophoresis that have been made over the past three years. ICP as a means of controlling the distribution of the ions and electric field in a microfluidic device has rapidly expanded its areas of application. Recent advancements have focused on the development of ion-permselective materials with tunable dimensions and surface chemistry, adaptation to paper microfluidics, higher-throughput device geometries, and coupling ICP with other separation (isotachophoresis and dielectrophoresis) and fluidic (valve and droplet microfluidic) strategies. These studies have made great strides toward solving real-world problems such as low-cost and rapid analysis, accessible desalination technology, and single-cell research tools.
在这篇综述中，我们讨论了过去三年中基于离子浓差极化（ICP）的浓缩、分离、脱盐和介电泳方面的进展。ICP 作为控制微流控装置中离子和电场分布的一种手段，其应用领域迅速扩大。最近的进展集中在开发具有可调尺寸和表面化学性质的离子选择性材料、适应纸微流控、更高通量的器件几何形状以及将 ICP 与其他分离（等速电泳和介电泳）和流体（阀和液滴微流控）策略相结合。这些研究朝着解决实际问题迈出了重要一步，例如低成本和快速分析、可访问的脱盐技术以及单细胞研究工具。
