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[痢疾和沙门氏菌感染诊断的临床形态学标准]

[Clinico-morphological criteria of diagnosis of dysentery and Salmonella infections].

作者信息

Shuvalova E P, Polotskiĭ V Iu

出版信息

Klin Med (Mosk). 1989 Nov;67(11):112-7.

PMID:2696830
Abstract

Clinical symptoms and laboratory findings have been evaluated for 108 patients with intestinal infection associated with apparent colitic syndrome. Differential diagnosis between dysentery and salmonellosis was not an easy task even though clinical signs of the diseases appeared different. Dysentery ran with tenesmus, sigmoid pain and spasms. Symptoms of gastritis, intoxication, dehydration, hepatomegaly predominated in salmonellosis. In obscure cases colonic biopsy can be helpful due to high sensitivity of immunofluorescence in histological sections. Morphological diagnostic criteria comprise intensive microbial invasion, pronounced immunomorphological reaction in superficial epithelium of the colon for dysentery and macrophagal affection of the colonic mucosa plate for salmonellosis.

摘要

对108例伴有明显结肠炎综合征的肠道感染患者的临床症状和实验室检查结果进行了评估。尽管痢疾和沙门氏菌病的临床症状有所不同,但两者之间的鉴别诊断并非易事。痢疾伴有里急后重、乙状结肠疼痛和痉挛。沙门氏菌病则以胃炎、中毒、脱水、肝肿大症状为主。在一些不明原因的病例中,由于免疫荧光在组织切片中的高敏感性,结肠活检可能会有所帮助。形态学诊断标准包括:痢疾时强烈的微生物侵袭、结肠浅表上皮明显的免疫形态学反应,以及沙门氏菌病时结肠黏膜板的巨噬细胞病变。

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