Aung Eindra, Donald Maria, Williams Gail M, Coll Joseph R, Doi Suhail A R
School of Public Health, University of Queensland, Brisbane, Australia Research School of Population Health, Australian National University, Canberra, Australia.
Discipline of General Practice, School of Medicine, University of Queensland, Brisbane, Australia.
Int J Qual Health Care. 2016 Jun;28(3):306-10. doi: 10.1093/intqhc/mzw023. Epub 2016 Mar 10.
To examine the association of the Patient Assessment of Chronic Illness Care (PACIC) with health-related quality of life (HRQoL) and the modulating effect of patient activation on this association.
A population-based prospective cohort study of people with Type 2 diabetes in Queensland, Australia, using data from self-report questionnaires, collected annually from 2008 (n = 3761) to 2010 (n = 3040).
Predictors were the 20-item PACIC (dichotomized at the score of 3), and the 13-item Patient Activation Measure (PAM), dichotomized into activation Levels 1 and 2 versus Levels 3 and 4. Analyses were restricted to participants whose PACIC and PAM categories did not change over 2 years of follow-up. Outcome variables were EQ-5D index and EQ VAS dichotomized at the uppermost quartile, and EQ-5D index also dichotomized at the median.
An inverse probability weighted Poisson regression with a log-link function and a binary response variable for each outcome was used to obtain risk ratios (RRs), and the interaction between PACIC and PAM was statistically modelled, taking into consideration patient characteristics and the respective baseline outcome variable.
The positive association between the PACIC and EQ VAS was seen only in participants with low activation (adjusted RR: 3.91; 95% CI: 1.40-10.95; P = 0.009), and not in those with high activation, indicating the non-synergistic interaction effect of the PACIC and PAM. This association was not found with EQ-5D index.
Chronic care received consistently over time can positively affect health status, and benefit patients with low activation.
探讨慢性病护理患者评估(PACIC)与健康相关生活质量(HRQoL)之间的关联,以及患者激活对该关联的调节作用。
基于澳大利亚昆士兰州2型糖尿病患者的人群前瞻性队列研究,使用2008年(n = 3761)至2010年(n = 3040)每年收集的自我报告问卷数据。
预测因素为20项PACIC(得分3分为二分法)和13项患者激活量表(PAM),分为激活水平1和2与水平3和4。分析仅限于在2年随访期间PACIC和PAM类别未发生变化的参与者。结局变量为EQ-5D指数和EQ VAS,以最高四分位数进行二分法划分,EQ-5D指数也以中位数进行二分法划分。
采用具有对数链接函数和每个结局的二元响应变量的逆概率加权泊松回归来获得风险比(RRs),并对PACIC和PAM之间的相互作用进行统计建模,同时考虑患者特征和各自的基线结局变量。
PACIC与EQ VAS之间的正相关仅在低激活参与者中可见(调整后的RR:3.91;95%CI:1.40 - 10.95;P = 0.009),而在高激活参与者中未发现,表明PACIC和PAM之间存在非协同相互作用效应。EQ-5D指数未发现这种关联。
长期持续接受的慢性病护理可对健康状况产生积极影响,并使低激活患者受益。