Tuveson R W, Larson R A, Marley K A, Wang G R, Berenbaum M R
Photochem Photobiol. 1989 Dec;50(6):733-8. doi: 10.1111/j.1751-1097.1989.tb02903.x.
Sanguinarine chloride, a quaternary salt of a benzophenanthrene alkaloid, was phototoxic to catalase-deficient strains of Escherichia coli but not to Trichoplusia ni (cabbage looper moth larvae), an insect with high levels of catalase activity. Chemical analyses confirm that sanguinarine is an efficient producer of H2O2. This differential toxicity suggests that the mode of phototoxic action involves production of H2O2 which could be detoxified in many organisms by catalase.
氯化血根碱，一种苯并菲啶生物碱的季铵盐，对过氧化氢酶缺陷型大肠杆菌菌株具有光毒性，但对过氧化氢酶活性高的昆虫粉纹夜蛾（甘蓝尺蠖幼虫）没有光毒性。化学分析证实血根碱是过氧化氢的有效产生者。这种不同的毒性表明，光毒性作用模式涉及过氧化氢的产生，而过氧化氢在许多生物体中可被过氧化氢酶解毒。
