Krivjanský V, Obernauerová M, Ulrichová J, Simánek V, Subík J
Department of Microbiology and Virology, Faculty of Sciences, Comenius University, Bratislava, Slovak Republic.
FEMS Microbiol Lett. 1994 Jul 1;120(1-2):87-91. doi: 10.1016/0378-1097(94)00180-4.
Chelerythrine and sanguinarine, two structurally related benzo/c/phenanthridine alkaloids, prevented growth of yeast cells in medium containing either glucose or non-fermentable carbon sources. At concentrations permitting growth of the yeast Saccharomyces cerevisiae, chelerythrine, but not sanquinarine, induced cytoplasmic respiration-deficient mutants. The petite clones that were analysed exhibited suppressiveness and contained different fragments of the wild-type mitochondrial genome.
白屈菜红碱和血根碱是两种结构相关的苯并[c]菲啶生物碱，它们在含有葡萄糖或不可发酵碳源的培养基中可阻止酵母细胞生长。在允许酿酒酵母生长的浓度下，白屈菜红碱而非血根碱可诱导细胞质呼吸缺陷型突变体。所分析的小菌落克隆表现出抑制性，并含有野生型线粒体基因组的不同片段。
