Stefancic Martin, Vidmar Gaj, Blagus Rok
University Rehabilitation Institute, Linhartova 51, SI-1000, Ljubljana, Slovenia.
Faculty of Medicine, Institute for Biostatistics and Medical Informatics, University of Ljubljana, Ljubljana, Slovenia.
Muscle Nerve. 2016 Oct;54(4):702-8. doi: 10.1002/mus.25103. Epub 2016 Jul 26.
The probability and degree of muscle recovery after lesions of long peripheral nerves have not been assessed quantitatively.
Twelve adults with closed injuries of the fibular division of the sciatic nerve with complete denervation of associated muscles were followed-up for 2-10 years. The onset of reinnervation was detected electromyographically. Calf circumference and maximum voluntary isometric contraction (MVIC) of foot dorsiflexion were measured on both sides during 2-4 visits.
Reinnervation occurred in 11 patients after an average of 13 months. MVIC on the affected side was 2%-27% of that on the unaffected side (average 11%) and remained stable for the following 2-3 years. Correlations and mixed-model regressions confirmed that the degree of recovery was negatively associated with duration of denervation.
Reinnervation occurs in about 90% of patients within about 1 year. About 10% of baseline dorsiflexion strength is permanently recovered, which is functionally relevant. Muscle Nerve, 2016 Muscle Nerve 54: -, 2016 Muscle Nerve 54: 702-708, 2016.
长周围神经损伤后肌肉恢复的概率和程度尚未进行定量评估。
对12例坐骨神经腓侧支闭合性损伤且相关肌肉完全失神经支配的成年人进行了2至10年的随访。通过肌电图检测神经再支配的起始情况。在2至4次就诊期间测量双侧小腿围度和足背屈的最大自主等长收缩（MVIC）。
11例患者平均在13个月后出现神经再支配。患侧的MVIC为健侧的2%至27%（平均11%），并在接下来的2至3年保持稳定。相关性分析和混合模型回归证实恢复程度与失神经支配持续时间呈负相关。
约90%的患者在约1年内出现神经再支配。约10%的背屈基线力量可永久恢复，这具有功能相关性。《肌肉与神经》，2016年 《肌肉与神经》54卷：-，2016年 《肌肉与神经》54卷：702 - 708页，2016年
