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居家医院环境中的静脉抗菌治疗:来自西班牙门诊胃肠外抗菌治疗登记处的数据。

Intravenous antimicrobial therapy in the hospital-at-home setting: data from the Spanish Outpatient Parenteral Antimicrobial Therapy Registry.

作者信息

Mirón-Rubio Manuel, González-Ramallo Víctor, Estrada-Cuxart Oriol, Sanroma-Mendizábal Pedro, Segado-Soriano Antonio, Mujal-Martínez Abel, Del Río-Vizoso Manuel, García-Lezcano Mario, Martín-Blanco Natalia, Florit-Serra Lidia, Gil-Bermejo Mercè

机构信息

Hospital Universitario de Torrejón, Torrejón de Ardoz, Madrid, Spain.

Hospital General Universitario Gregorio Marañón, Madrid, Madrid, Spain.

出版信息

Future Microbiol. 2016;11(3):375-90. doi: 10.2217/fmb.15.141. Epub 2016 Mar 14.

Abstract

AIM

To evaluate outpatient parenteral antimicrobial therapy (OPAT) in the hospital-at-home (HaH) model, using data from a Spanish registry.

PATIENTS & METHODS: We describe episodes/characteristics of patients receiving OPAT.

RESULTS

Four thousand and five patients were included (mean age 66.2 years), generating 4416 HaH episodes, 4474 infections and 5088 antibiotic treatments. Most patients were from the hospital admission ward and emergency department. Respiratory, urinary and intra-abdominal infections predominated (72%). Forty-six different antimicrobials were used, including combinations of ≥ 2 drugs (20.7%). Most HaH episodes had a successful outcome (91%).

CONCLUSION

Our findings are similar to those obtained previously although our study case profiles differ, suggesting that disease processes of greater severity and complexity can be treated using this healthcare model, without compromising patient safety.

摘要

目的

利用西班牙登记处的数据,评估家庭医院模式下的门诊胃肠外抗菌治疗(OPAT)。

患者与方法

我们描述了接受OPAT治疗的患者的病例/特征。

结果

纳入4005例患者(平均年龄66.2岁),产生4416次家庭医院治疗病例、4474例感染和5088次抗生素治疗。大多数患者来自医院入院病房和急诊科。呼吸道、泌尿系统和腹腔内感染占主导(72%)。使用了46种不同的抗菌药物,包括≥2种药物的联合使用(20.7%)。大多数家庭医院治疗病例取得了成功(91%)。

结论

尽管我们的研究病例概况不同,但我们的研究结果与之前获得的结果相似,这表明使用这种医疗模式可以治疗更严重和复杂的疾病过程,而不会损害患者安全。

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