居家医院中多重耐药菌感染的治疗。
Treatment of infections caused by multi-resistant microorganisms in hospital at home units.
机构信息
Manuel Mirón-Rubio, Unidad de Hospitalización a Domicilio. Hospital Universitario de Torrejón. Spain.
出版信息
Rev Esp Quimioter. 2021 Sep;34 Suppl 1(Suppl1):18-21. doi: 10.37201/req/s01.05.2021. Epub 2021 Sep 30.
Abstract
Hospital at home units allow the treatment of moderate and severe infections by administering intravenous antibiotics to patients who would otherwise have to remain hospitalised. Increasing antibiotic resistance adds an element of difficulty to outpatient treatment of infections because multiple daily doses of antimicrobials or combinations of antimicrobials are sometimes required. This manuscript discusses some of the challenges of outpatient management of infections with multidrug-resistant microorganisms and shows the main antibiotic resistances and the outcomes of treatment of these infections in Spanish home hospitalisation units.
摘要
家庭医院病房可以为那些原本需要住院治疗的中度和重度感染患者提供静脉内抗生素治疗。抗生素耐药性的增加为感染的门诊治疗增加了难度，因为有时需要每日多次给予抗菌药物或联合使用抗菌药物。本文讨论了门诊管理多重耐药微生物感染的一些挑战，并展示了西班牙家庭住院病房中这些感染的主要抗生素耐药性和治疗结果。
相似文献
1
Treatment of infections caused by multi-resistant microorganisms in hospital at home units.居家医院中多重耐药菌感染的治疗。
Rev Esp Quimioter. 2021 Sep;34 Suppl 1(Suppl1):18-21. doi: 10.37201/req/s01.05.2021. Epub 2021 Sep 30.
2
Safety and effectiveness of home intravenous antibiotic therapy for multidrug-resistant bacterial infections.家庭静脉注射抗生素治疗多重耐药细菌感染的安全性和有效性。
Eur J Clin Microbiol Infect Dis. 2015 Jun;34(6):1125-33. doi: 10.1007/s10096-015-2330-0. Epub 2015 Feb 6.
3
Usefulness of Hospital at Home in nosocomial infections: advantages and limitations.居家医院模式在医院感染中的作用：优势与局限
Rev Esp Quimioter. 2017 Sep;30 Suppl 1:61-65.
4
Nanoantibiotics: A Novel Rational Approach to Antibiotic Resistant Infections.纳米抗生素：一种针对抗生素耐药感染的新型合理方法。
Curr Drug Metab. 2019;20(9):720-741. doi: 10.2174/1389200220666190806142835.
5
[Linezolid in the treatment of antibiotic-resistant gram-positive infections of the musculoskeletal system].利奈唑胺治疗肌肉骨骼系统耐抗生素革兰氏阳性菌感染
Acta Chir Orthop Traumatol Cech. 2006 Oct;73(5):329-33.
6
Characteristics of Microbial Factors of Healthcare-Associated Infections Including Multidrug-Resistant Pathogens and Antibiotic Consumption at the University Intensive Care Unit in Poland in the Years 2011-2018.2011-2018 年波兰大学重症监护病房医源性感染相关的微生物因素特征，包括多药耐药病原体和抗生素使用情况。
Int J Environ Res Public Health. 2020 Sep 23;17(19):6943. doi: 10.3390/ijerph17196943.
7
Efficacy and safety of ceftazidime-avibactam compared to other antimicrobials for the treatment of infections caused by carbapenem-resistant Klebsiella pneumoniae strains, a systematic review and meta-analysis.头孢他啶-阿维巴坦与其他抗菌药物治疗碳青霉烯类耐药肺炎克雷伯菌引起的感染的疗效和安全性：系统评价和荟萃分析。
Microb Pathog. 2023 Jun;179:106090. doi: 10.1016/j.micpath.2023.106090. Epub 2023 Mar 31.
8
Neonatal infections due to multi-resistant strains: Epidemiology, current treatment, emerging therapeutic approaches and prevention.多重耐药菌株引起的新生儿感染：流行病学、当前治疗方法、新兴治疗手段及预防
Clin Chim Acta. 2015 Dec 7;451(Pt A):71-7. doi: 10.1016/j.cca.2015.02.038. Epub 2015 Mar 4.
9
Investigating forthcoming strategies to tackle deadly superbugs: current status and future vision.研究应对致命超级细菌的未来策略：现状与未来展望。
Expert Rev Anti Infect Ther. 2022 Oct;20(10):1309-1332. doi: 10.1080/14787210.2022.2122442. Epub 2022 Sep 28.
10
Using a simple point-prevalence survey to define appropriate antibiotic prescribing in hospitalised children across the UK.采用简单的现患率调查来确定英国住院儿童的合理抗生素处方。
BMJ Open. 2016 Nov 3;6(11):e012675. doi: 10.1136/bmjopen-2016-012675.
引用本文的文献
1
Analysis of the Frequency, Antibiotic Susceptibility, and Related Genes among Foodborne Pathogenic Bacteria Isolated from Hospital Refrigerators in Tehran, Iran.伊朗德黑兰医院冰箱中分离出的食源性病原体细菌的频率、抗生素敏感性及相关基因分析
Iran J Public Health. 2024 Mar;53(3):680-690. doi: 10.18502/ijph.v53i3.15150.
本文引用的文献
1
Antimicrobial management in community acquired pneumonia in hospital at home: Is there room for improvement?居家医院获得性肺炎的抗菌药物管理：是否有改进的空间？
Enferm Infecc Microbiol Clin (Engl Ed). 2021 Jun-Jul;39(6):271-275. doi: 10.1016/j.eimce.2021.04.005. Epub 2021 May 4.
2
Continuous infusion of antibiotics using elastomeric pumps in the hospital at home setting.家庭病床中使用弹性泵持续输注抗生素。
Rev Esp Quimioter. 2021 Jun;34(3):200-206. doi: 10.37201/req/122.2020. Epub 2021 Mar 16.
3
Plasma concentrations resulting from continuous infusion of meropenem in a community-based outpatient program: A case series.社区门诊计划中美罗培南持续输注的血药浓度：病例系列。
Am J Health Syst Pharm. 2020 Dec 4;77(24):2074-2080. doi: 10.1093/ajhp/zxaa319.
4
Factors associated with successful completion of outpatient parenteral antibiotic therapy in an area with a high prevalence of multidrug-resistant bacteria: 30-day hospital admission and mortality rates.多药耐药菌高发地区门诊肠外抗生素治疗成功完成的相关因素：30 天住院率和死亡率。
PLoS One. 2020 Nov 18;15(11):e0241595. doi: 10.1371/journal.pone.0241595. eCollection 2020.
5
Systematic review of stability data pertaining to selected antibiotics used for extended infusions in outpatient parenteral antimicrobial therapy (OPAT) at standard room temperature and in warmer climates.系统评价与标准室温及温暖气候下门诊患者使用的延长输注的选定抗生素稳定性数据有关的研究。
Eur J Hosp Pharm. 2020 Mar;27(2):65-72. doi: 10.1136/ejhpharm-2019-001875. Epub 2019 Jun 20.
6
Evaluation of Inpatient Antimicrobial Regimens for Readmitted Outpatient Parenteral Antimicrobial Therapy Patients Receiving Daptomycin or Ertapenem for Ease of Administration.对因给药便利性而接受达托霉素或厄他培南治疗的再入院门诊胃肠外抗菌治疗患者的住院抗菌治疗方案的评估。
Open Forum Infect Dis. 2019 Nov 19;6(12):ofz496. doi: 10.1093/ofid/ofz496. eCollection 2019 Dec.
7
Quality Indicators for Appropriate Outpatient Parenteral Antimicrobial Therapy in Adults: A Systematic Review and RAND-modified Delphi Procedure.成人门诊患者适宜的肠外抗菌治疗质量指标：系统评价和 RAND 改良 Delphi 程序。
Clin Infect Dis. 2020 Mar 3;70(6):1075-1082. doi: 10.1093/cid/ciz362.
8
Executive summary of outpatient parenteral antimicrobial therapy: Guidelines of the Spanish Society of Clinical Microbiology and Infectious Diseases and the Spanish Domiciliary Hospitalisation Society.门诊胃肠外抗菌治疗执行摘要：西班牙临床微生物学与传染病学会及西班牙家庭住院治疗学会指南
Enferm Infecc Microbiol Clin (Engl Ed). 2019 Jun-Jul;37(6):405-409. doi: 10.1016/j.eimc.2018.03.012. Epub 2018 May 18.
9
Intravenous antimicrobial therapy in the hospital-at-home setting: data from the Spanish Outpatient Parenteral Antimicrobial Therapy Registry.居家医院环境中的静脉抗菌治疗：来自西班牙门诊胃肠外抗菌治疗登记处的数据。
Future Microbiol. 2016;11(3):375-90. doi: 10.2217/fmb.15.141. Epub 2016 Mar 14.
10
Self-administered outpatient parenteral antimicrobial therapy (S-OPAT) for infective endocarditis: a safe and effective model.感染性心内膜炎的自我管理门诊胃肠外抗菌治疗（S-OPAT）：一种安全有效的模式。
Eur J Intern Med. 2015 Mar;26(2):131-6. doi: 10.1016/j.ejim.2015.01.001. Epub 2015 Jan 14.
Zotero 插件