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Opinion: Focus on preclinical sex differences will not address women's and men's health disparities.观点:关注临床前的性别差异无法解决女性和男性的健康差距问题。
Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13419-20. doi: 10.1073/pnas.1516958112.
2
Treatment of Cardiovascular Risk Factors in Women.
Curr Med Chem. 2015;22(31):3580-96. doi: 10.2174/0929867322666151001122213.
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Mitochondrial DNA maintenance: an appraisal.线粒体DNA维持:一项评估。
Mol Cell Biochem. 2015 Nov;409(1-2):283-305. doi: 10.1007/s11010-015-2532-x. Epub 2015 Aug 19.
4
Sex differences in mechanisms, presentation and management of ischaemic heart disease.缺血性心脏病在发病机制、临床表现及治疗方面的性别差异。
Atherosclerosis. 2015 Jul;241(1):157-68. doi: 10.1016/j.atherosclerosis.2015.04.802. Epub 2015 Apr 27.
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Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.全球、地区和国家按年龄、性别划分的 240 种死因的全死因和特定死因死亡率,1990-2013 年:2013 年全球疾病负担研究的系统分析。
Lancet. 2015 Jan 10;385(9963):117-71. doi: 10.1016/S0140-6736(14)61682-2. Epub 2014 Dec 18.
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Mechanisms involved in developmental programming of hypertension and renal diseases. Gender differences.高血压和肾脏疾病发育编程涉及的机制。性别差异。
Horm Mol Biol Clin Investig. 2014 May;18(2):63-77. doi: 10.1515/hmbci-2013-0054.
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Effect of preeclampsia on placental function: influence of sexual dimorphism, microRNA's and mitochondria.子痫前期对胎盘功能的影响:性二态性、微小RNA和线粒体的作用
Adv Exp Med Biol. 2014;814:133-46. doi: 10.1007/978-1-4939-1031-1_12.
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Estradiol treatment promotes cardiac stem cell (CSC)-derived growth factors, thus improving CSC-mediated cardioprotection after acute ischemia/reperfusion.雌二醇治疗可促进心脏干细胞(CSC)衍生的生长因子,从而改善急性缺血/再灌注后 CSC 介导的心脏保护作用。
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Sex-specific T-cell regulation of angiotensin II-dependent hypertension.性别特异性 T 细胞对血管紧张素 II 依赖性高血压的调节作用。
Hypertension. 2014 Sep;64(3):573-82. doi: 10.1161/HYPERTENSIONAHA.114.03663. Epub 2014 Jun 16.
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Sex differences in T-lymphocyte tissue infiltration and development of angiotensin II hypertension.T 淋巴细胞组织浸润和血管紧张素 II 型高血压发展中的性别差异。
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Report of the National Heart, Lung, and Blood Institute Working Group on Sex Differences Research in Cardiovascular Disease: Scientific Questions and Challenges.

作者信息

Maric-Bilkan Christine, Arnold Arthur P, Taylor Doris A, Dwinell Melinda, Howlett Susan E, Wenger Nanette, Reckelhoff Jane F, Sandberg Kathryn, Churchill Gary, Levin Ellis, Lundberg Martha S

机构信息

From the Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (C.M.-B., M.S.L.); Department of Integrative Biology and Physiology, University of California at Los Angeles (A.P.A.); Department of Regenerative Medicine, Texas Heart Institute, Houston (D.A.T.); Department of Physiology, Medical College of Wisconsin, Milwaukee (M.D.); Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada (S.E.H.); Cardiovascular Physiology, University of Manchester, Manchester, United Kingdom (S.E.H.); Department of Medicine, Emory University School of Medicine, Atlanta, GA (N.W.); Department of Physiology, University of Mississippi Medical Center, Jackson (J.F.R.); Department of Medicine, Georgetown University Medical Center, Washington, DC (K.S.); The Jackson Laboratory, Bar Harbor, ME (G.C.); and Department of Endocrinology, Diabetes, and Metabolism, University of California, Irvine (E.L.).

出版信息

Hypertension. 2016 May;67(5):802-7. doi: 10.1161/HYPERTENSIONAHA.115.06967. Epub 2016 Mar 14.

DOI:10.1161/HYPERTENSIONAHA.115.06967
PMID:26975706
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4833564/
Abstract
摘要