[Alport综合征患者活体亲属供肾肾移植]
[Kidney allotransplantation from alive related donor in patients with Alport syndrome].
作者信息
Goriaĭnov V A, Kaabak M M, Babenko N N, Morozova M M, Aganesov A P, Panin V V, Platova E N, Dymova O V
机构信息
Acad. B.V. Petrovsky Russian Research Surgery Center, Moscow.
出版信息
Khirurgiia (Mosk). 2016(1):50-54. doi: 10.17116/hirurgia2016150-54.
AIM
To evaluate the results of kidney transplantation from alive related donor in patients with Alport syndrome and to compare with those in patients with kidney hypoplasia.
MATERIAL AND METHODS
We have analyzed 8 and 27 medical records of patients with Alport syndrome and kidney hypoplasia respectively. Following parameters were used - Kaplan-Meier survival analysis, Wilcox overall risk, percentage of transplants loss and mortality (Fisher's exact test calculation).
RESULTS
It is concluded that percentage of transplants loss and mortality rate as well as overall survival and risk were similar in both groups.
CONCLUSION
Despite risk of anti-GBM nephritis development in patients with Alport syndrome results are comparable with those after transplatation for chronic renal failure caused by other reasons.
目的
评估亲属活体供肾移植治疗奥尔波特综合征患者的效果，并与肾发育不全患者的效果进行比较。
材料与方法
我们分别分析了8例奥尔波特综合征患者和27例肾发育不全患者的病历。采用以下参数——Kaplan-Meier生存分析、Wilcox总体风险、移植失败百分比和死亡率（Fisher精确检验计算）。
结果
得出两组的移植失败百分比、死亡率以及总体生存率和风险相似的结论。
结论
尽管奥尔波特综合征患者有发生抗肾小球基底膜肾炎的风险，但其结果与因其他原因导致的慢性肾衰竭移植后的结果相当。
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