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欧洲老年慢性肾脏病管理多学科指南的优先主题

Priority topics for European multidisciplinary guidelines on the management of chronic kidney disease in older adults.

作者信息

van der Veer Sabine N, van Biesen Wim, Bernaert Pascale, Bolignano Davide, Brown Edwina A, Covic Adrian, Farrington Ken, Jager Kitty J, Kooman Jeroen, Macías-Núñez Juan F, Mooney Andrew, van Munster Barbara C, Topinkova Eva, Van Den Noortgate Nele J A, Wirnsberger Gerhard, Michel Jean-Pierre, Nistor Ionut

机构信息

European Renal Best Practice Methods Support Team, Ghent University Hospital, Ghent, Belgium.

Health eResearch Centre @ Farr Institute for Health Informatics Research, University of Manchester, Vaughan House, Portsmouth Street, Manchester, M13 9GB, UK.

出版信息

Int Urol Nephrol. 2016 Jun;48(6):859-69. doi: 10.1007/s11255-016-1257-4. Epub 2016 Mar 17.

Abstract

PURPOSE

To identify and prioritize potential topics to be addressed in the development of European multidisciplinary guidelines on the management of chronic kidney disease stage 3b-5 in older patients.

METHODS

We composed a list of 47 potential guideline topics by reviewing the literature, consulting online 461 nephrologists and 107 geriatricians, and obtaining expert input. A multidisciplinary panel of twelve experts then prioritized the topics during a face-to-face consensus meeting, following a nominal group technique structure with two voting rounds. Topics were rated on a 9-point scale ranging from 1 ('not at all important') to 9 ('critically important').

RESULTS

The highest rating (median; range) was assigned to 'Screening and referral' (8.5; 2.0). Eight topics shared the second highest rating with a median priority score of 8.0 (2.0) and included 'Starting dialysis or not' and 'Accurate assessment of renal function.' 'Targets for and treatment of diabetes' received the lowest rating with (3.0; 6.0).

CONCLUSIONS

This joint initiative of the European Renal Association-European Dialysis Transplant Association (ERA-EDTA) and the European Union Geriatric Medicine Society (EUGMS) prioritized the development of guidance on interdisciplinary referral of older patients with chronic kidney disease stage 3b-5. Future guidance will therefore focus on identifying prognostic scores to predict death and progression to end-stage renal disease, as well as accurate tests for assessment of renal function in older kidney patients. This will contribute to more informed treatment decision making in this growing patient population.

摘要

目的

确定并优先排序欧洲关于老年慢性肾脏病3b - 5期管理的多学科指南制定中要解决的潜在主题。

方法

我们通过查阅文献、在线咨询461名肾病学家和107名老年病学家并获取专家意见,列出了47个潜在的指南主题。然后,一个由12名专家组成的多学科小组在面对面的共识会议上,按照名义小组技术结构进行两轮投票,对这些主题进行优先排序。主题按照从1(“完全不重要”)到9(“极其重要”)的9分制进行评分。

结果

“筛查与转诊”获得了最高评分(中位数;范围)(8.5;2.0)。八个主题并列第二高评分,中位数优先得分是8.0(2.0),包括“是否开始透析”和“肾功能的准确评估”。“糖尿病的治疗目标”获得了最低评分(3.0;6.0)。

结论

欧洲肾脏协会 - 欧洲透析移植协会(ERA - EDTA)和欧洲老年医学学会(EUGMS)的这项联合倡议,优先考虑了针对老年慢性肾脏病3b - 5期患者跨学科转诊指南的制定。因此,未来的指南将侧重于确定预测死亡和进展至终末期肾病的预后评分,以及针对老年肾病患者肾功能评估的准确检测方法。这将有助于在这一不断增长的患者群体中做出更明智的治疗决策。

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