定义临床实践指南的关键问题：一种开发临床相关问题的新方法。
Defining key questions for clinical practice guidelines: a novel approach for developing clinically relevant questions.
作者信息
Chakraborty Samantha, Brijnath Bianca, Dermentzis Jacinta, Mazza Danielle
机构信息
Department of General Practice, Faculty of Medicine, Nursing and Health Sciences, School of Primary and Allied Health Care, Monash University, Building 1, 270 Ferntree Gully Road, Notting Hill, Victoria, 3150, Australia.
National Ageing Research Institute Ltd, Parkville, Australia.
出版信息
Health Res Policy Syst. 2020 Sep 29;18(1):113. doi: 10.1186/s12961-020-00628-3.
BACKGROUND
There is no standardised protocol for developing clinically relevant guideline questions. We aimed to create such a protocol and to apply it to developing a new guideline.
METHODS
We reviewed international guideline manuals and, through consensus, combined steps for developing clinical questions to produce a best-practice protocol that incorporated qualitative research. The protocol was applied to develop clinical questions for a guideline for general practitioners.
RESULTS
A best-practice protocol incorporating qualitative research was created. Using the protocol, we developed 10 clinical questions that spanned diagnosis, management and follow-up.
CONCLUSIONS
Guideline developers can apply this protocol to develop clinically relevant guideline questions.
背景
目前尚无用于制定具有临床相关性的指南问题的标准化方案。我们旨在创建这样一种方案，并将其应用于制定一项新的指南。
方法
我们查阅了国际指南手册，并通过共识，整合了制定临床问题的步骤，以生成一个纳入定性研究的最佳实践方案。该方案被应用于为全科医生指南制定临床问题。
结果
创建了一个纳入定性研究的最佳实践方案。使用该方案，我们制定了10个涵盖诊断、管理和随访的临床问题。
结论
指南制定者可以应用此方案来制定具有临床相关性的指南问题。
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