• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

定义临床实践指南的关键问题：一种开发临床相关问题的新方法。

Defining key questions for clinical practice guidelines: a novel approach for developing clinically relevant questions.

作者信息

Chakraborty Samantha, Brijnath Bianca, Dermentzis Jacinta, Mazza Danielle

机构信息

Department of General Practice, Faculty of Medicine, Nursing and Health Sciences, School of Primary and Allied Health Care, Monash University, Building 1, 270 Ferntree Gully Road, Notting Hill, Victoria, 3150, Australia.

National Ageing Research Institute Ltd, Parkville, Australia.

出版信息

Health Res Policy Syst. 2020 Sep 29;18(1):113. doi: 10.1186/s12961-020-00628-3.

DOI:10.1186/s12961-020-00628-3
PMID:32993665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7523054/
Abstract

BACKGROUND

There is no standardised protocol for developing clinically relevant guideline questions. We aimed to create such a protocol and to apply it to developing a new guideline.

METHODS

We reviewed international guideline manuals and, through consensus, combined steps for developing clinical questions to produce a best-practice protocol that incorporated qualitative research. The protocol was applied to develop clinical questions for a guideline for general practitioners.

RESULTS

A best-practice protocol incorporating qualitative research was created. Using the protocol, we developed 10 clinical questions that spanned diagnosis, management and follow-up.

CONCLUSIONS

Guideline developers can apply this protocol to develop clinically relevant guideline questions.

摘要

背景

目前尚无用于制定具有临床相关性的指南问题的标准化方案。我们旨在创建这样一种方案，并将其应用于制定一项新的指南。

方法

我们查阅了国际指南手册，并通过共识，整合了制定临床问题的步骤，以生成一个纳入定性研究的最佳实践方案。该方案被应用于为全科医生指南制定临床问题。

结果

创建了一个纳入定性研究的最佳实践方案。使用该方案，我们制定了10个涵盖诊断、管理和随访的临床问题。

结论

指南制定者可以应用此方案来制定具有临床相关性的指南问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f1e/7523054/fb699231cb13/12961_2020_628_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f1e/7523054/fb699231cb13/12961_2020_628_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f1e/7523054/fb699231cb13/12961_2020_628_Fig1_HTML.jpg

相似文献

1
Defining key questions for clinical practice guidelines: a novel approach for developing clinically relevant questions.定义临床实践指南的关键问题：一种开发临床相关问题的新方法。
Health Res Policy Syst. 2020 Sep 29;18(1):113. doi: 10.1186/s12961-020-00628-3.
2
How to develop cost-conscious guidelines.如何制定注重成本的指南。
Health Technol Assess. 2001;5(16):1-69. doi: 10.3310/hta5160.
3
Impact of patient involvement on clinical practice guideline development: a parallel group study.患者参与对临床实践指南制定的影响：一项平行组研究。
Implement Sci. 2018 Apr 16;13(1):55. doi: 10.1186/s13012-018-0745-6.
4
The Effectiveness of Integrated Care Pathways for Adults and Children in Health Care Settings: A Systematic Review.综合护理路径在医疗环境中对成人和儿童的有效性：一项系统评价。
JBI Libr Syst Rev. 2009;7(3):80-129. doi: 10.11124/01938924-200907030-00001.
5
[Guidelines 2.0: systematic development of a comprehensive checklist for a successful guideline enterprise].[指南2.0：成功开展指南工作的综合清单的系统制定]
Recenti Prog Med. 2015 Jun;106(6):249-79. doi: 10.1701/1884.20552.
6
Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome.国际循证指南关于多囊卵巢综合征评估和管理的推荐意见。
Fertil Steril. 2018 Aug;110(3):364-379. doi: 10.1016/j.fertnstert.2018.05.004. Epub 2018 Jul 19.
7
Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome.多囊卵巢综合征评估与管理的国际循证指南推荐意见。
Hum Reprod. 2018 Sep 1;33(9):1602-1618. doi: 10.1093/humrep/dey256.
8
Addressing implementation challenges during guideline development - a case study of Swedish national guidelines for methods of preventing disease.应对指南制定过程中的实施挑战——以瑞典疾病预防方法国家指南为例
BMC Health Serv Res. 2015 Jan 22;15:19. doi: 10.1186/s12913-014-0672-4.
9
Priority setting in guideline development: article 2 in Integrating and coordinating efforts in COPD guideline development. An official ATS/ERS workshop report.指南制定中的优先事项设定：《COPD 指南制定中整合和协调工作》一文的第 2 部分。美国胸科学会/欧洲呼吸学会官方研讨会报告。
Proc Am Thorac Soc. 2012 Dec;9(5):225-8. doi: 10.1513/pats.201208-055ST.
10
Use of qualitative research as evidence in the clinical guideline program of the National Institute for Health and Clinical Excellence.定性研究在英国国家卫生与临床优化研究所临床指南计划中的应用。
Int J Evid Based Healthc. 2009 Sep;7(3):169-72. doi: 10.1111/j.1744-1609.2009.00135.x.

引用本文的文献

1
ChatGPT Responses to Clinical Questions in the Japan Atherosclerosis Society Guidelines for Prevention of Atherosclerotic Cardiovascular Disease 2022.ChatGPT对《2022年日本动脉粥样硬化协会动脉粥样硬化性心血管疾病预防指南》中临床问题的回答。
J Atheroscler Thromb. 2025 May 1;32(5):567-579. doi: 10.5551/jat.65240. Epub 2024 Oct 30.
2
Association of Area Deprivation With Primary Hypertension Diagnosis Among Youth Medicaid Recipients in Delaware.特拉华州青年医疗补助计划受助人原发性高血压诊断与地区贫困程度的关联。
JAMA Netw Open. 2023 Mar 1;6(3):e233012. doi: 10.1001/jamanetworkopen.2023.3012.
3
Knowledge, attitudes and behaviours surrounding preconception and pregnancy health: an Australian cross-sectional survey.

本文引用的文献

1
What clinical challenges are associated with diagnosing and managing work-related mental health conditions? A qualitative study in general practice.与诊断和管理与工作相关的心理健康状况相关的临床挑战有哪些？一般实践中的定性研究。
BMJ Open. 2020 Aug 16;10(8):e037734. doi: 10.1136/bmjopen-2020-037734.
2
A common framework of steps and criteria for prioritizing topics for evidence syntheses: a systematic review.一种常见的证据综合主题优先级制定步骤和标准框架：系统综述。
J Clin Epidemiol. 2020 Apr;120:67-85. doi: 10.1016/j.jclinepi.2019.12.009. Epub 2019 Dec 14.
3
Clinicians' Perspectives on Barriers to Discussing Infertility and Fertility Preservation With Young Women With Cancer.
关于孕前和孕期健康的知识、态度和行为：澳大利亚横断面调查。
BMJ Open. 2023 Jan 3;13(1):e065055. doi: 10.1136/bmjopen-2022-065055.
4
Ensuring quality in contextualised cancer management guidelines for resource-constraint settings: using a systematic approach.确保资源有限环境下制定的癌症管理指南具有质量：使用系统方法。
BMJ Glob Health. 2022 Aug;7(8). doi: 10.1136/bmjgh-2022-009584.
5
Publishing clinical prActice GuidelinEs (PAGE): Recommendations from editors and reviewers.发表临床实践指南（PAGE）：编辑和审稿人的建议。
Chin J Traumatol. 2022 Nov;25(6):312-316. doi: 10.1016/j.cjtee.2022.06.007. Epub 2022 Jun 27.
6
Implementing work-related Mental health guidelines in general PRacticE (IMPRovE): a protocol for a hybrid III parallel cluster randomised controlled trial.在一般实践中实施与工作相关的心理健康指南（IMPRovE）：一项混合 III 平行集群随机对照试验的方案。
Implement Sci. 2021 Aug 4;16(1):77. doi: 10.1186/s13012-021-01146-8.
临床医生对与年轻癌症女性讨论不孕不育和生育力保存的障碍的看法。
JAMA Netw Open. 2019 Nov 1;2(11):e1914511. doi: 10.1001/jamanetworkopen.2019.14511.
4
Prioritization approaches in the development of health practice guidelines: a systematic review.卫生实践指南制定中的优先排序方法：系统评价。
BMC Health Serv Res. 2019 Oct 15;19(1):692. doi: 10.1186/s12913-019-4567-2.
5
The WHO-INTEGRATE evidence to decision framework version 1.0: integrating WHO norms and values and a complexity perspective.世界卫生组织-整合证据到决策框架第1.0版：整合世界卫生组织的规范和价值观以及复杂性视角。
BMJ Glob Health. 2019 Jan 25;4(Suppl 1):e000844. doi: 10.1136/bmjgh-2018-000844. eCollection 2019.
6
Clinical Practice Guidelines: What's Next?临床实践指南：接下来会怎样？
JAMA. 2018 Aug 28;320(8):757-758. doi: 10.1001/jama.2018.9660.
7
Development of rapid guidelines: 3. GIN-McMaster Guideline Development Checklist extension for rapid recommendations.快速指南的制定：3. 用于快速推荐的 GIN-McMaster 指南制定清单扩展。
Health Res Policy Syst. 2018 Jul 13;16(1):63. doi: 10.1186/s12961-018-0330-0.
8
More Than a Tick Box: Medical Checklist Development, Design, and Use.不止是打勾：医学检查表的开发、设计与使用
Anesth Analg. 2018 Jan;126(1):223-232. doi: 10.1213/ANE.0000000000002286.
9
Using Qualitative Research to Inform Development of Professional Guidelines: A Case Study of the Society of Critical Care Medicine Family-Centered Care Guidelines.运用定性研究为专业指南的制定提供信息：以危重病医学会家庭为中心的护理指南为例。
Crit Care Med. 2017 Aug;45(8):1352-1358. doi: 10.1097/CCM.0000000000002523.
10
GRADE Evidence to Decision (EtD) frameworks for adoption, adaptation, and de novo development of trustworthy recommendations: GRADE-ADOLOPMENT.用于采用、改编和全新制定可靠建议的GRADE证据到决策（EtD）框架：GRADE-ADOLOPMENT。
J Clin Epidemiol. 2017 Jan;81:101-110. doi: 10.1016/j.jclinepi.2016.09.009. Epub 2016 Oct 3.