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母乳喂养时长与贫血之间存在关联吗?

Is there any relation between Duration of breastfeeding and anemia?

作者信息

Dalili H, Baghersalimi A, Dalili S, Pakdaman F, Hassanzadeh Rad A, Abbasi Kakroodi M, Rezvany S M, Koohmanaei Sh

机构信息

Department of Pediatrics, Breastfeeding Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Pediatrics Growth Disorders Research Center, School of Medicine, 17th Shahrivar Hospital, Guilan University of Medical Sciences, Rasht, Iran.

出版信息

Iran J Ped Hematol Oncol. 2015;5(4):218-26. Epub 2015 Dec 10.

Abstract

BACKGROUND

In the early months of life, Breastfeeding increases chance of survival, reduces recovery time after disease and mortality due to infections such as diarrhea and acute respiratory infections. However, infants who are exclusively breast-fed for more than 6 months in developing countries may be at increased risk of anemia. Therefore, the aim of study was to assess the relation between duration of breastfeeding and anemia.

MATERIALS AND METHODS

In this analytical cross-sectional study, 400 neonates registered in primary health care system since birth time. Complete blood count and serum ferritin were obtained. Data were analyzed by chi- square test and regression analysis. P-value less than 0.05 was considered significant and 95% confidence interval was noted.

RESULTS

Results of this study showed that 199 infants were anemic (Hemoglobin (Hb) concentration <11 mg/dl). Ten percent of anemic patients reported Ferritin< 12ng/dl and %25 of anemic children had iron deficiency anemia (IDA). In Binominal logistic regression, merely kind of delivery and duration of breastfeeding were effective factors. Binominal logistic regression also showed that natural vaginal delivery and exclusive breastfeeding up to 6 months had a significant influence on anemia. Exclusive breast feeding for 6 months or more increased the likelihood of anemia. In addition, 4 months exclusive breastfeeding decreased 0.686 fold the likelihood of anemia.

CONCLUSION

According to the results, it seems that revision of health program recommendations for iron supplementation can be constructive. National planning to promote the level of knowledge regarding natural vaginal delivery and appropriate period for clamping can be recommended.

摘要

背景

在生命的最初几个月,母乳喂养可提高生存几率,缩短患病后的恢复时间,并降低因腹泻和急性呼吸道感染等感染导致的死亡率。然而,在发展中国家,纯母乳喂养超过6个月的婴儿患贫血的风险可能会增加。因此,本研究的目的是评估母乳喂养持续时间与贫血之间的关系。

材料与方法

在这项分析性横断面研究中,选取了自出生起就在初级卫生保健系统登记的400名新生儿。进行了全血细胞计数和血清铁蛋白检测。数据通过卡方检验和回归分析进行分析。P值小于0.05被认为具有统计学意义,并记录了95%的置信区间。

结果

本研究结果显示,199名婴儿贫血(血红蛋白(Hb)浓度<11mg/dl)。10%的贫血患者血清铁蛋白<12ng/dl,25%的贫血儿童患有缺铁性贫血(IDA)。在二项逻辑回归中,只有分娩方式和母乳喂养持续时间是影响因素。二项逻辑回归还显示,自然阴道分娩和6个月内纯母乳喂养对贫血有显著影响。纯母乳喂养6个月或更长时间会增加患贫血的可能性。此外,4个月纯母乳喂养使患贫血的可能性降低了0.686倍。

结论

根据研究结果,似乎修订关于铁补充剂的健康计划建议可能具有建设性。可以建议国家制定计划,提高对自然阴道分娩和适当结扎时间的认识水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe9c/4779157/b99ac502b49b/ijpho-5-218-g001.jpg

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