一家中国医院微生物抗微生物药物耐药性的三年调查。
A three-year survey of the antimicrobial resistance of microorganisms at a Chinese hospital.
作者信息
Tang Jing, Wang Lili, Xi Yufei, Liu Gaolin
机构信息
Department of Clinical Pharmacy, Shanghai First People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200080, P.R. China.
Department of Blood Transfusion, Shanghai First People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200080, P.R. China.
出版信息
Exp Ther Med. 2016 Mar;11(3):731-736. doi: 10.3892/etm.2016.2983. Epub 2016 Jan 12.
The present retrospective study aimed to investigate the antibiotic susceptibility of bacteria at Shanghai First People's Hospital (Shanghai, China) between 2009 and 2011. An increasing trend of antibiotic resistance was observed in this hospital between 2009 and 2011. , and were the most prevalent resistant strains. Antimicrobial susceptibility was detected using standard Kirby-Bauer disk diffusion and analyzed using World Health Organization software. was demonstrated to be the most prevalent bacterium in the present survey between 2009 and 2011 (16.2, 20.0 and 19.6%, respectively); followed by (13.5, 13.3 and 10.6%, respectively) and . Notably, >70% of and 70% of were resistant to common antibiotics; whereas 60% of and 20% of were resistant to the majority of the antibiotics investigated. In 2011, exhibited a resistance rate of 55.6% against levofloxacin and exhibited a 53.2% resistance rate. The present survey demonstrated an increasing trend in bacterial resistance against antibiotics; therefore, more stringent guidelines for antibiotics should be advocated.
本回顾性研究旨在调查2009年至2011年期间上海第一人民医院（中国上海）细菌的抗生素敏感性。2009年至2011年期间，该医院观察到抗生素耐药性呈上升趋势。 、 和 是最常见的耐药菌株。采用标准的 Kirby-Bauer 纸片扩散法检测抗菌药物敏感性，并使用世界卫生组织软件进行分析。在本次2009年至2011年的调查中， 被证明是最常见的细菌（分别为16.2%、20.0%和19.6%）；其次是 （分别为13.5%、13.3%和10.6%）和 。值得注意的是，超过70%的 和70%的 对常用抗生素耐药；而60%的 和20%的 对大多数所调查的抗生素耐药。2011年， 对左氧氟沙星的耐药率为55.6%， 的耐药率为53.2%。本次调查表明细菌对抗生素的耐药性呈上升趋势；因此，应倡导更严格的抗生素使用指南。
Zotero 插件