甲氟喹耐药性的高级分子检测
Advanced Molecular Detection of Malarone Resistance.
作者信息
Talundzic Eldin, Plucinski Mateusz M, Biliya Shweta, Silva-Flannery Luciana M, Arguin Paul M, Halsey Eric S, Barnwell John W, Vannberg Fredrik, Udhayakumar Venkatachalam
机构信息
Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA Atlanta Research and Education Foundation, Veterans Affairs Medical Center, Atlanta, Georgia, USA
Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA President's Malaria Initiative, Atlanta, Georgia, USA.
出版信息
Antimicrob Agents Chemother. 2016 May 23;60(6):3821-3. doi: 10.1128/AAC.00171-16. Print 2016 Jun.
Abstract
The rapid emergence of drug-resistant malaria parasites during the course of an infection remains a major challenge for providing accurate treatment guidelines. This is particularly important in cases of malaria treatment failure. Using a previously well-characterized case of malaria treatment failure, we show the utility of using next-generation sequencing for early detection of the rise and selection of a previously reported atovaquone-proguanil (malarone) drug resistance-associated mutation.
摘要
在感染过程中耐药疟原虫的迅速出现仍然是提供准确治疗指南的一项重大挑战。这在疟疾治疗失败的病例中尤为重要。利用一个先前已充分表征的疟疾治疗失败病例，我们展示了使用新一代测序技术早期检测先前报道的与阿托伐醌-氯胍（malarone）耐药相关突变的出现和选择的效用。
相似文献
1
Advanced Molecular Detection of Malarone Resistance.
Antimicrob Agents Chemother. 2016 May 23;60(6):3821-3. doi: 10.1128/AAC.00171-16. Print 2016 Jun.
2
Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria.
Malar J. 2002 Feb 8;1:1. doi: 10.1186/1475-2875-1-1.
3
Confirmation of emergence of mutations associated with atovaquone-proguanil resistance in unexposed Plasmodium falciparum isolates from Africa.
Malar J. 2006 Oct 4;5:82. doi: 10.1186/1475-2875-5-82.
4
Atovaquone/Proguanil Resistance in an Imported Malaria Case in Chile.
Am J Trop Med Hyg. 2021 Mar 29;104(5):1811-1813. doi: 10.4269/ajtmh.20-1095.
5
Malarone treatment failure not associated with previously described mutations in the cytochrome b gene.
Malar J. 2004 Jun 8;3:14. doi: 10.1186/1475-2875-3-14.
6
Analyses of cytochrome b mutations in Plasmodium falciparum isolates in Thai-Myanmar border.
Travel Med Infect Dis. 2007 Mar;5(2):132-4. doi: 10.1016/j.tmaid.2006.07.002. Epub 2006 Sep 20.
7
Late clinical failure associated with cytochrome b codon 268 mutation during treatment of falciparum malaria with atovaquone-proguanil in traveller returning from Congo.
Malar J. 2020 Jan 21;19(1):37. doi: 10.1186/s12936-020-3126-y.
8
Mutations in the Plasmodium falciparum cytochrome b gene are associated with delayed parasite recrudescence in malaria patients treated with atovaquone-proguanil.
Malar J. 2008 Nov 20;7:240. doi: 10.1186/1475-2875-7-240.
9
In vitro atovaquone/proguanil susceptibility and characterization of the cytochrome b gene of Plasmodium falciparum from different endemic regions of Thailand.
Malar J. 2008 Jan 28;7:23. doi: 10.1186/1475-2875-7-23.
10
Screening for mutations related to atovaquone/proguanil resistance in treatment failures and other imported isolates of Plasmodium falciparum in Europe.
J Infect Dis. 2004 Nov 1;190(9):1541-6. doi: 10.1086/424469. Epub 2004 Sep 28.
引用本文的文献
1
Comparative analysis of targeted next-generation sequencing for Plasmodium falciparum drug resistance markers.
Sci Rep. 2022 Apr 1;12(1):5563. doi: 10.1038/s41598-022-09474-5.
2
Molecular surveillance of drug resistance: Plasmodium falciparum artemisinin resistance single nucleotide polymorphisms in Kelch protein propeller (K13) domain from Southern Pakistan.
Malar J. 2021 Apr 7;20(1):176. doi: 10.1186/s12936-021-03715-0.
3
Machine learning and applications in microbiology.
FEMS Microbiol Rev. 2021 Sep 8;45(5). doi: 10.1093/femsre/fuab015.
4
Selection of Cytochrome Mutants Is Rare among Plasmodium falciparum Patients Failing Treatment with Atovaquone-Proguanil in Cambodia.
Antimicrob Agents Chemother. 2021 Feb 17;65(3). doi: 10.1128/AAC.01249-20.
5
Amplicon deep sequencing of kelch13 in Plasmodium falciparum isolates from Senegal.
Malar J. 2020 Mar 30;19(1):134. doi: 10.1186/s12936-020-03193-w.
6
Targeted deep amplicon sequencing of kelch 13 and cytochrome b in Plasmodium falciparum isolates from an endemic African country using the Malaria Resistance Surveillance (MaRS) protocol.
Parasit Vectors. 2020 Mar 14;13(1):137. doi: 10.1186/s13071-020-4005-7.
7
Atovaquone-Proguanil in Combination With Artesunate to Treat Multidrug-Resistant Malaria in Cambodia: An Open-Label Randomized Trial.
Open Forum Infect Dis. 2019 Sep 4;6(9):ofz314. doi: 10.1093/ofid/ofz314. eCollection 2019 Sep.
8
Next-Generation Sequencing and Bioinformatics Protocol for Malaria Drug Resistance Marker Surveillance.
Antimicrob Agents Chemother. 2018 Mar 27;62(4). doi: 10.1128/AAC.02474-17. Print 2018 Apr.
9
Emergence and Spread of Mutations Associated with Artemisinin Resistance in Plasmodium falciparum Parasites in 12 Thai Provinces from 2007 to 2016.
Antimicrob Agents Chemother. 2018 Mar 27;62(4). doi: 10.1128/AAC.02141-17. Print 2018 Apr.
10
Molecular Epidemiology of Plasmodium falciparum kelch13 Mutations in Senegal Determined by Using Targeted Amplicon Deep Sequencing.
Antimicrob Agents Chemother. 2017 Feb 23;61(3). doi: 10.1128/AAC.02116-16. Print 2017 Mar.
本文引用的文献
1
A comprehensive benchmarking study of protocols and sequencing platforms for 16S rRNA community profiling.
BMC Genomics. 2016 Jan 14;17:55. doi: 10.1186/s12864-015-2194-9.
2
How next-generation sequencing and multiscale data analysis will transform infectious disease management.
Clin Infect Dis. 2015 Dec 1;61(11):1695-702. doi: 10.1093/cid/civ670. Epub 2015 Aug 6.
3
A platform for leveraging next generation sequencing for routine microbiology and public health use.
Health Inf Sci Syst. 2015 Feb 24;3(Suppl 1 HISA Big Data in Biomedicine and Healthcare 2013 Con):S7. doi: 10.1186/2047-2501-3-S1-S7. eCollection 2015.
4
Novel Mutation in Cytochrome B of Plasmodium falciparum in One of Two Atovaquone-Proguanil Treatment Failures in Travelers Returning From Same Site in Nigeria.
Open Forum Infect Dis. 2014 Aug 5;1(2):ofu059. doi: 10.1093/ofid/ofu059. eCollection 2014 Sep.
5
Emergence of resistance to atovaquone-proguanil in malaria parasites: insights from computational modeling and clinical case reports.
Antimicrob Agents Chemother. 2014 Aug;58(8):4504-14. doi: 10.1128/AAC.02550-13. Epub 2014 May 27.
6
Routine use of microbial whole genome sequencing in diagnostic and public health microbiology.
PLoS Pathog. 2012;8(8):e1002824. doi: 10.1371/journal.ppat.1002824. Epub 2012 Aug 2.
7
Evaluation of genomic high-throughput sequencing data generated on Illumina HiSeq and genome analyzer systems.
Genome Biol. 2011 Nov 8;12(11):R112. doi: 10.1186/gb-2011-12-11-r112.
8
Ultrasensitive detection of rare mutations using next-generation targeted resequencing.
Nucleic Acids Res. 2012 Jan;40(1):e2. doi: 10.1093/nar/gkr861. Epub 2011 Oct 19.
9
Tracking origins and spread of sulfadoxine-resistant Plasmodium falciparum dhps alleles in Thailand.
Antimicrob Agents Chemother. 2011 Jan;55(1):155-64. doi: 10.1128/AAC.00691-10. Epub 2010 Oct 18.
10
Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: diagnostic and clinical implications.
J Mol Diagn. 2010 Jul;12(4):425-32. doi: 10.2353/jmoldx.2010.090188. Epub 2010 Apr 29.
Zotero 插件