Ebrahem Rawaa, Ahmed Brittany, Kadhem Salam, Truong Quoc
Internal Medicine, University of Kansas School of Medicine-Wichita.
Cancer Center of Kansas.
Cureus. 2016 Feb 2;8(2):e476. doi: 10.7759/cureus.476.
Chronic myeloid leukemia (CML), a hematologic malignancy characterized by unregulated growth of myelogenous leukocytes, typically presents with symptoms of fatigue, anorexia, and splenomegaly. Laboratory studies often reveal a significant leukocytosis with neutrophilia. A moderate thrombocytosis may be present, but is not usually problematic. The following case discusses a patient who presented with syncope, a convulsive episode, and non ST-segment myocardial infarction secondary to symptomatic thrombocytosis of 2.5 million cells/microL. She was treated with plateletpheresis and subsequently experienced resolution of symptoms. Ultimately, a diagnosis of CML with an atypical presentation of the disease was identified in this patient.
慢性髓性白血病（CML）是一种血液系统恶性肿瘤，其特征为骨髓性白细胞不受控制地生长，通常表现为疲劳、厌食和脾肿大等症状。实验室检查常显示白细胞显著增多伴中性粒细胞增多。可能存在中度血小板增多，但通常无问题。以下病例讨论了一名患者，该患者因250万个细胞/微升的症状性血小板增多继发晕厥、惊厥发作和非ST段心肌梗死。她接受了血小板单采术治疗，随后症状得到缓解。最终，该患者被确诊为患有非典型表现的慢性髓性白血病。
