McCarthy L J, Graves V L, Eigen H, McGuire W A
Indiana University School of Medicine, Indianapolis 46202-5283, USA.
Transfus Med. 1991 Sep;1(3):187-9. doi: 10.1111/j.1365-3148.1991.tb00030.x.
This report describes the dramatic reduction in the platelet count and ablation of symptoms by consecutive platelet apheresis in a young girl with CML who presented with an extremely high platelet count of 10,320 x 10(9)/l. Extreme thrombocytosis, although quite rare, can be symptomatic and life-threatening in paediatric patients and should be considered an emergency. The mechanical removal of platelets by apheresis is effective therapy and should begin as soon as possible.
