Hu Xiaobin, Bai Yana, Pu Hongquan, Zhang Kai, Cheng Ning, Li Haiyan, Shen Xiping, Li Fuxiu, Ren Xiaowei, Zhu Jinbing, Zheng Shan, Wang Minzhen, Dai Min
Institute of Epidemiology and Biostatistics, School of Public Health, Center for Cancer Prevention and Control, Lanzhou University, Lanzhou 730000, China.
Workers'Hospital of Jinchuan Group Company Limited, Jinchang 737100, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2016 Mar;37(3):321-4. doi: 10.3760/cma.j.issn.0254-6450.2016.03.005.
To understand the current status of the disease burden of liver cancer in Jinchang cohort.
All the liver cancer death data from 2001 to 2013 and medical records of liver cancer cases from 2001 to 2010 in Jinchang cohort were collected for the analyses of the mortality, standardized mortality, potential years of life lost (PYLL) and working PYLL (WPYLL) associated with liver cancer. Spearman correlation and the average growth rate were used to analyze the trends.
A total of 207 liver cancer deaths occurred in Jinchang cohort from 2001 to 2013, accounting for 16.68% of total cancer deaths. There were 259 liver cancer inpatients, accounting for 6.79% of the total cancer cases inpatients, in which 83 died (32.05%). Liver cancer death mainly occurred in males, accounting for 88.89%, and the liver cancer deaths in females accounted for 11.11%. The standardized mortality rate was 42.32/100,000 in males and 15.31/100,000 in females. The growth rate of liver cancer mortality was 5.62% from 2001 to 2013. Liver cancer deaths mainly occurred in age groups 60-69 years (26.57%) and 50-59 years (24.15%). The PYLL was 2906.76 person-years, the average PYLL was 14.04 years. The WPYLL was 1477.00 person-years and the average WPYLL was 7.14 years. The direct economic burden of liver cancer was 6270.78 Yuan per person, 301.75 Yuan per day. The average stay of hospitalization was 21.32 days.
The mortality rate of liver cancer is increasing and the disease burden is still heavy.
了解金昌队列人群肝癌疾病负担现状。
收集金昌队列人群2001年至2013年全部肝癌死亡资料以及2001年至2010年肝癌病例的病历资料，分析肝癌的死亡率、标准化死亡率、潜在寿命损失年数（PYLL）和工作寿命损失年数（WPYLL）。采用Spearman相关分析和平均增长率分析趋势。
2001年至2013年金昌队列人群共发生肝癌死亡207例，占全部癌症死亡的16.68%。肝癌住院患者259例，占全部癌症住院病例的6.79%，其中83例死亡（32.05%）。肝癌死亡主要发生在男性，占88.89%，女性肝癌死亡占11.11%。男性标准化死亡率为42.32/10万，女性为15.31/10万。2001年至2013年肝癌死亡率增长率为5.62%。肝癌死亡主要发生在60 - 69岁年龄组（26.57%）和50 - 59岁年龄组（24.15%）。PYLL为2906.76人年，平均PYLL为14.04年。WPYLL为1477.00人年，平均WPYLL为7.14年。肝癌直接经济负担为每人6270.78元，每日301.75元。平均住院天数为21.32天。
肝癌死亡率呈上升趋势，疾病负担仍较重。
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