Department of Nephrology and Organ Transplantation, CHU Rangueil, Toulouse, France.
INSERM U1043, IFR-BMT, CHU Purpan, Toulouse, France.
Liver Int. 2016 Apr;36(4):467-72. doi: 10.1111/liv.13037.
Hepatitis E virus can cause acute, fulminant and chronic hepatitis and has been associated with a range of extrahepatic manifestations. Guillain-Barré syndrome, neuralgic amyotrophy and encephalitis are the main neurological manifestations associated with acute and chronic hepatitis E virus infection. Renal injuries have been also reported, including membranoproliferative glomerulonephritis with or without cryoglobulinemia and membranous glomerulonephritis. Acute pancreatitis, haematological disorders and other autoimmune extrahepatic manifestations of hepatitis E virus, such as myocarditis and thyroiditis, have been also reported. In this comprehensive article, we review all published reports describing hepatitis E virus-associated extrahepatic manifestations.
戊型肝炎病毒可引起急性、暴发性和慢性肝炎，并与一系列肝外表现有关。吉兰-巴雷综合征、神经痛性肌萎缩和脑炎是与急性和慢性戊型肝炎病毒感染相关的主要神经系统表现。肾损伤也有报道，包括伴有或不伴有冷球蛋白血症的膜增生性肾小球肾炎和膜性肾小球肾炎。急性胰腺炎、血液系统疾病和戊型肝炎病毒的其他自身免疫性肝外表现，如心肌炎和甲状腺炎，也有报道。在这篇综合文章中，我们回顾了所有已发表的描述戊型肝炎病毒相关肝外表现的报告。
