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Therapy: Risks associated with chronic PPI use - signal or noise?

作者信息

Kia Leila, Kahrilas Peter J

机构信息

Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, 60611 USA.

出版信息

Nat Rev Gastroenterol Hepatol. 2016 May;13(5):253-4. doi: 10.1038/nrgastro.2016.44. Epub 2016 Mar 16.

DOI:10.1038/nrgastro.2016.44
PMID:27006255
Abstract
摘要

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Association of Proton Pump Inhibitors With Risk of Dementia: A Pharmacoepidemiological Claims Data Analysis.质子泵抑制剂与痴呆风险的关联：基于药物流行病学索赔数据分析。
JAMA Neurol. 2016 Apr;73(4):410-6. doi: 10.1001/jamaneurol.2015.4791.
2
Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease.质子泵抑制剂的使用与慢性肾脏病风险
JAMA Intern Med. 2016 Feb;176(2):238-46. doi: 10.1001/jamainternmed.2015.7193.
3
Low Prevalence of Hypomagnesemia in Long-term Recipients of Proton Pump Inhibitors in a Managed Care Cohort.
胃食管反流病：内镜评估与治疗的最新进展
Gastroenterol Rep (Oxf). 2021 Oct 18;9(5):383-391. doi: 10.1093/gastro/goab029. eCollection 2021 Oct.
4
Indian consensus on gastroesophageal reflux disease in adults: A position statement of the Indian Society of Gastroenterology.印度成人胃食管反流病共识：印度胃肠病学会立场声明
Indian J Gastroenterol. 2019 Oct;38(5):411-440. doi: 10.1007/s12664-019-00979-y. Epub 2019 Dec 5.
5
Maintenance use of non-steroidal anti-inflammatory drugs and risk of gastrointestinal cancer in a nationwide population-based cohort study in Sweden.瑞典一项基于全国人群的队列研究中，非甾体抗炎药的维持使用与胃肠道癌症风险
BMJ Open. 2018 Jul 7;8(7):e021869. doi: 10.1136/bmjopen-2018-021869.
6
Abnormal esophageal acid exposure on high-dose proton pump inhibitor therapy is common in systemic sclerosis patients.大剂量质子泵抑制剂治疗时，系统性硬化症患者食管酸暴露异常常见。
Neurogastroenterol Motil. 2018 Feb;30(2). doi: 10.1111/nmo.13247. Epub 2017 Nov 6.
7
Emerging dilemmas in the diagnosis and management of gastroesophageal reflux disease.胃食管反流病诊断与管理中的新困境
F1000Res. 2017 Sep 25;6:1748. doi: 10.12688/f1000research.11918.1. eCollection 2017.
8
Proton Pump Inhibitors in Gastroesophageal Reflux Disease: Friend or Foe.质子泵抑制剂在胃食管反流病中的作用：益友还是劲敌？
Curr Gastroenterol Rep. 2017 Sep;19(9):46. doi: 10.1007/s11894-017-0586-5.
9
ACG and CAG Clinical Guideline: Management of Dyspepsia.ACG 和 CAG 临床指南：消化不良的管理。
Am J Gastroenterol. 2017 Jul;112(7):988-1013. doi: 10.1038/ajg.2017.154. Epub 2017 Jun 20.
10
When is proton pump inhibitor use appropriate?质子泵抑制剂何时使用合适？
BMC Med. 2017 Feb 21;15(1):36. doi: 10.1186/s12916-017-0804-x.
质子泵抑制剂长期使用者中低镁血症的发生率较低。
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4
Proton Pump Inhibitor Usage and the Risk of Myocardial Infarction in the General Population.质子泵抑制剂的使用与普通人群心肌梗死风险
PLoS One. 2015 Jun 10;10(6):e0124653. doi: 10.1371/journal.pone.0124653. eCollection 2015.
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Risk of community-acquired pneumonia with outpatient proton-pump inhibitor therapy: a systematic review and meta-analysis.门诊质子泵抑制剂治疗与社区获得性肺炎风险：一项系统评价和荟萃分析。
PLoS One. 2015 Jun 4;10(6):e0128004. doi: 10.1371/journal.pone.0128004. eCollection 2015.
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A nationwide nested case-control study indicates an increased risk of acute interstitial nephritis with proton pump inhibitor use.一项全国性巢式病例对照研究表明，使用质子泵抑制剂会增加急性间质性肾炎的风险。
Kidney Int. 2014 Oct;86(4):837-44. doi: 10.1038/ki.2014.74. Epub 2014 Mar 19.
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Proton pump inhibitors and acute kidney injury: a nested case-control study.质子泵抑制剂与急性肾损伤：一项巢式病例对照研究。
BMC Nephrol. 2013 Jul 16;14:150. doi: 10.1186/1471-2369-14-150.
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False alarms and pseudo-epidemics: the limitations of observational epidemiology.假警报和假性流行：观察性流行病学的局限性。
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Long-term proton pump inhibitor therapy and risk of hip fracture.长期质子泵抑制剂治疗与髋部骨折风险
JAMA. 2006 Dec 27;296(24):2947-53. doi: 10.1001/jama.296.24.2947.
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Risk of Clostridium difficile diarrhea among hospital inpatients prescribed proton pump inhibitors: cohort and case-control studies.住院患者中开具质子泵抑制剂处方后发生艰难梭菌腹泻的风险：队列研究和病例对照研究
CMAJ. 2004 Jul 6;171(1):33-8. doi: 10.1503/cmaj.1040876.