Bera Tushar Kanti
Department of Computational Science and Engineering, Yonsei University, Seoul 120749, Republic of Korea.
J Med Eng. 2014;2014:381251. doi: 10.1155/2014/381251. Epub 2014 Jun 17.
Under the alternating electrical excitation, biological tissues produce a complex electrical impedance which depends on tissue composition, structures, health status, and applied signal frequency, and hence the bioelectrical impedance methods can be utilized for noninvasive tissue characterization. As the impedance responses of these tissue parameters vary with frequencies of the applied signal, the impedance analysis conducted over a wide frequency band provides more information about the tissue interiors which help us to better understand the biological tissues anatomy, physiology, and pathology. Over past few decades, a number of impedance based noninvasive tissue characterization techniques such as bioelectrical impedance analysis (BIA), electrical impedance spectroscopy (EIS), electrical impedance plethysmography (IPG), impedance cardiography (ICG), and electrical impedance tomography (EIT) have been proposed and a lot of research works have been conducted on these methods for noninvasive tissue characterization and disease diagnosis. In this paper BIA, EIS, IPG, ICG, and EIT techniques and their applications in different fields have been reviewed and technical perspective of these impedance methods has been presented. The working principles, applications, merits, and demerits of these methods has been discussed in detail along with their other technical issues followed by present status and future trends.
在交变电激励下,生物组织会产生一个复杂的电阻抗,该电阻抗取决于组织的组成、结构、健康状况以及所施加信号的频率,因此生物电阻抗方法可用于无创组织表征。由于这些组织参数的阻抗响应会随所施加信号的频率而变化,在宽频带上进行的阻抗分析能提供更多关于组织内部的信息,这有助于我们更好地理解生物组织的解剖学、生理学和病理学。在过去几十年里,已经提出了许多基于阻抗的无创组织表征技术,如生物电阻抗分析(BIA)、电阻抗谱(EIS)、电阻抗体积描记法(IPG)、阻抗心动图(ICG)和电阻抗断层成像(EIT),并且针对这些用于无创组织表征和疾病诊断的方法开展了大量研究工作。本文对BIA、EIS、IPG、ICG和EIT技术及其在不同领域的应用进行了综述,并阐述了这些阻抗方法的技术前景。详细讨论了这些方法的工作原理、应用、优缺点以及其他技术问题,随后介绍了其现状和未来趋势。