Serpa Marianna Sampaio, Costa-Neto Hugo, de Oliveira Patrícia Teixeira, da Silveira Éricka Janine Dantas, de Medeiros Ana Miryam Costa
Postgraduate Program in Oral Pathology, Department of Dentistry, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho, 1787, Lagoa Nova, Natal, Rio Grande do Norte, CEP 59.056-000, Brazil.
Eur Arch Otorhinolaryngol. 2016 Oct;273(10):3439-41. doi: 10.1007/s00405-016-4006-5. Epub 2016 Mar 23.
Granular cell tumor (GCT) is an uncommon benign soft tissue neoplasm, which usually presents as a solitary nodule, appearing especially in the tongue. There are few cases of multiple oral GCT in the English-language literature, with only three cases reported in the last 20 years. This report describes a case of two oral GCT in a young patient and provides a literature review from 1995 to 2015. Clinical characteristics of the reviewed cases were retrieved and compared with the present case. Exceptionally, the current case was the only one that occurred in an adolescent and solely affected the oral cavity. Besides the oral cavity, the other cases also observed GCT lesions in the skin. Although rare, it is important to know multiple oral GCT clinical and histopathological characteristics so they can be correctly diagnosed, treated and followed up.
颗粒细胞瘤（GCT）是一种罕见的良性软组织肿瘤，通常表现为单个结节，尤其多见于舌部。英文文献中关于多发口腔颗粒细胞瘤的病例很少，过去20年仅有3例报道。本报告描述了一名年轻患者发生两例口腔颗粒细胞瘤的病例，并对1995年至2015年的文献进行了综述。检索了所综述病例的临床特征并与本病例进行比较。特别的是，本病例是唯一发生在青少年且仅累及口腔的病例。除口腔外，其他病例还在皮肤发现颗粒细胞瘤病变。尽管罕见，但了解多发口腔颗粒细胞瘤的临床和组织病理学特征很重要，以便能对其进行正确诊断、治疗和随访。
