Muehlberg Fabian, Toepper Agnieszka, Fritschi Simone, Prothmann Marcel, Schulz-Menger Jeanette
Working Group on Cardiovascular Magnetic Resonance, Experimental and Clinical Research Center-a joint cooperation between the Charité Medical Faculty and the Max-Delbrück Center for Molecular Medicine; HELIOS Hospital Berlin-Buch, Department of Cardiology and Nephrology, Berlin, Germany.
J Thorac Imaging. 2016 Nov;31(6):336-347. doi: 10.1097/RTI.0000000000000199.
Infiltrative cardiomyopathies are a heterogenous group of diseases that typically lead to restrictive cardiac dysfunction. Due to similar phenotypes, accurate diagnosis is challenging without invasive endomyocardial biopsy which has historically been considered mandatory. Cardiac magnetic resonance (CMR) has been well established in the diagnostic workup of patients with suspected cardiomyopathies due to its unique capability for tissue differentiation and its unsurpassed accuracy in defining cardiac morphology and function. The increasing variety of CMR techniques has generated both excitement and uncertainty with regard to their potential clinical use and its role vis-à-vis conventional noninvasive imaging techniques. The purpose of this review is to give an overview of established and emerging CMR techniques and typical image characteristics of the most commonly encountered infiltrative cardiomyopathies.
浸润性心肌病是一组异质性疾病,通常会导致限制性心脏功能障碍。由于表型相似,在没有进行侵入性心内膜活检(历史上一直被认为是必需的)的情况下,准确诊断具有挑战性。心脏磁共振成像(CMR)因其独特的组织分辨能力以及在定义心脏形态和功能方面无与伦比的准确性,已在疑似心肌病患者的诊断检查中得到广泛应用。CMR技术种类的不断增加,引发了人们对其潜在临床应用以及相对于传统非侵入性成像技术的作用的兴奋与不确定性。本综述的目的是概述已确立和新兴的CMR技术,以及最常见的浸润性心肌病的典型图像特征。