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自身免疫性甲状腺疾病所致心脏形态改变的心脏磁共振成像评估。

Evaluation of the Cardiac Morphologic Alterations Secondary to Autoimmune Thyroid Disorder Using Cardiac Magnetic Resonance Imaging.

机构信息

Institute of Radiology and Nuclear Medicine, Hanusch Hospital, Teaching Hospital of Medical University of Vienna.

Department of Nuclear Medicine with PET-Center, Wilhelminenspital, Vienna.

出版信息

J Thorac Imaging. 2018 Jul;33(4):254-259. doi: 10.1097/RTI.0000000000000306.

DOI:10.1097/RTI.0000000000000306
PMID:29076917
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6023583/
Abstract

PURPOSE

Thyroid functional disease is associated with clinically significant cardiovascular changes. The aim of this study was to assess changes in the cardiac magnetic resonance imaging of patients with autoimmune thyroid disorders (AITs).

MATERIALS AND METHODS

Forty patients with AIT (12 men, 28 women; age range, 20 to 82 y; mean age, 59 y) were identified and included in our study. In addition, 20 controls (12 men, 8 women; age range, 21 to 76 y; mean age, 50 y) without AIT or cardiac disorders were included.

RESULTS

In patients with AIT, the mean value calculated for the end diastolic volume was 161.2 mL, the mean end systolic volume value was 95.3 mL, and the mean left ventricular ejection fraction value was 45.2%. In comparing AIT patients with the control group, we found a significant difference in the end systolic volume, ejection fraction, stroke index, cardiac output, cardiac index, and left ventricular diameter (P<0.05).

CONCLUSIONS

We conclude that our data show that there is a correlation between thyroid function and cardiac function, as evaluated with cardiac magnetic resonance imaging. This can be useful in the diagnosis of cardiovascular changes associated with AIT.

摘要

目的

甲状腺功能疾病与临床显著的心血管变化有关。本研究旨在评估自身免疫性甲状腺疾病(AIT)患者心脏磁共振成像的变化。

材料与方法

我们确定并纳入了 40 名 AIT 患者(12 名男性,28 名女性;年龄 20 至 82 岁,平均年龄 59 岁),并纳入了 20 名无 AIT 或心脏疾病的对照者(12 名男性,8 名女性;年龄 21 至 76 岁,平均年龄 50 岁)。

结果

AIT 患者的舒张末期容积平均值为 161.2mL,收缩末期容积平均值为 95.3mL,左室射血分数平均值为 45.2%。与对照组相比,AIT 患者的收缩末期容积、射血分数、stroke index、心输出量、心指数和左心室直径存在显著差异(P<0.05)。

结论

我们的数据表明,甲状腺功能与心脏功能之间存在相关性,可通过心脏磁共振成像进行评估。这对于诊断与 AIT 相关的心血管变化可能具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb43/6023583/c798149b2c6a/rti-33-254-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb43/6023583/324e3584d61f/rti-33-254-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb43/6023583/2b96f166dc80/rti-33-254-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb43/6023583/c798149b2c6a/rti-33-254-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb43/6023583/324e3584d61f/rti-33-254-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb43/6023583/2b96f166dc80/rti-33-254-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb43/6023583/c798149b2c6a/rti-33-254-g004.jpg

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本文引用的文献

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Radiographic Evaluation of Valvular Heart Disease With Computed Tomography and Magnetic Resonance Correlation.
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Update on the Role of Cardiac Magnetic Resonance in Acquired Nonischemic Cardiomyopathies.心脏磁共振成像在获得性非缺血性心肌病中的作用最新进展
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Magnetic Resonance Imaging Applications on Infiltrative Cardiomyopathies.磁共振成像在浸润性心肌病中的应用
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Discordance between echocardiography and MRI in the assessment of mitral regurgitation severity: a prospective multicenter trial.超声心动图与 MRI 评估二尖瓣反流严重程度的不相符:一项前瞻性多中心试验。
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Expert consensus for multimodality imaging evaluation of adult patients during and after cancer therapy: a report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging.癌症治疗期间及之后成年患者多模态成像评估专家共识:美国超声心动图学会和欧洲心血管影像协会的报告
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Subclinical and overt thyroid dysfunction and risk of all-cause mortality and cardiovascular events: a large population study.亚临床和显性甲状腺功能障碍与全因死亡率及心血管事件风险:一项大型人群研究
J Clin Endocrinol Metab. 2014 Jul;99(7):2372-82. doi: 10.1210/jc.2013-4184. Epub 2014 Mar 21.
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