对于杜氏肌营养不良症患者，应多久评估一次从椅子上坐起和站起的情况？

How often should sitting and rising from a chair be evaluated in patients with Duchenne muscular dystrophy?

作者信息

Hukuda Michele Emy, Caromano Fátima Aparecida, Escorcio Renata, Carvalho Eduardo Vital de, Blascovi-Assis Silvana Maria, Voos Mariana Callil

机构信息

Universidade de São Paulo, Faculdade de Medicina, Laboratório de Fisioterapia e Comportamento, São Paulo SP, Brasil.

Universidade Mackenzie, Faculdade de Fisioterapia, São Paulo SP, Brasil.

出版信息

Arq Neuropsiquiatr. 2017 Sep;75(9):625-630. doi: 10.1590/0004-282X20170101.

DOI:10.1590/0004-282X20170101

PMID:28977142

Abstract

OBJECTIVE

To determine how often sitting/rising from a chair should be assessed in Duchenne muscular dystrophy (DMD) patients to avoid redundant/missing data.

METHODS

Sitting/rising from a chair was evaluated in 26 DMD children (5-12 yrs), in three-month intervals, over twelve months, with the Functional Evaluation Scale (domain sitting/rising from a chair). Scores were compared by effect sizes (ES) and standardized response means (SRM) (responsiveness analysis).

RESULTS

Sit-to-stand showed low-to-moderate responsiveness in three-month intervals (ES:0.23-0.32; SRM:0.36-0.68), moderate-to-high responsiveness in six-month intervals (ES:0.52-0.65; SRM:0.76-1.28), high responsiveness at nine-month (ES:0.84-0.91; SRM:1.26-1.64) and twelve-month intervals (ES:1.27; SRM:1.48). Stand-to-sit showed low responsiveness in three-month intervals (ES:0.26-0.49; SRM:0.37-0.42), moderate responsiveness in six-month intervals (ES:0.50-0.78; SRM:0.56-0.71), high responsiveness in nine-month (ES:0.94-1.00; SRM:0.84-1.02) and twelve-month intervals (ES:1.13; SRM:1.52).

CONCLUSION

Six months or longer intervals for reassessment are indicated to evaluate sitting/standing from a chair in DMD patients.

摘要

目的

确定对杜氏肌营养不良症（DMD）患者进行从椅子上坐起/站起评估的频率，以避免数据冗余/缺失。

方法

采用功能评估量表（从椅子上坐起/站起领域），对26名5至12岁的DMD儿童进行为期12个月、每三个月一次的从椅子上坐起/站起评估。通过效应量（ES）和标准化反应均值（SRM）比较评分（反应性分析）。

结果

从坐到站，三个月间隔时反应性为低到中度（ES：0.23 - 0.32；SRM：0.36 - 0.68），六个月间隔时为中度到高度（ES：0.52 - 0.65；SRM：0.76 - 1.28），九个月时为高度反应性（ES：0.84 - 0.91；SRM：1.26 - 1.64），十二个月间隔时为高度反应性（ES：1.27；SRM：1.48）。从站到坐，三个月间隔时反应性为低（ES：0.26 - 0.49；SRM：0.37 - 0.42），六个月间隔时为中度（ES：0.50 - 0.78；SRM：0.56 - 0.71），九个月时为高度反应性（ES：0.94 - 1.00；SRM：0.84 - 1.02），十二个月间隔时为高度反应性（ES：1.13；SRM：1.52）。