Emilson Christina, Demmelmaier Ingrid, Bergman Stefan, Lindberg Per, Denison Eva, Åsenlöf Pernilla
1 Department of Neuroscience, Uppsala University, Uppsala, Sweden.
2 Research and Development Center Spenshult, Halmstad, Sweden. Department of Public Health, and Community medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Clin Rehabil. 2017 Feb;31(2):186-196. doi: 10.1177/0269215516639356. Epub 2016 Jul 10.
To study the long-term outcomes of two interventions targeting patients with sub-acute and persistent pain in a primary care physiotherapy setting.
A 10-year follow-up of a two-armed randomised controlled trial, initially including 97 participants.
Tailored behavioural medicine treatment, applied in a physiotherapy context (experimental condition), and exercise-based physiotherapy (control condition).
Pain-related disability was the primary outcome. The maximum pain intensity, pain control, fear of movement, sickness-related absence (register data) and perceived benefit and confidence in coping with future pain problems were the secondary outcomes.
Forty-three (44%) participants responded to the follow-up survey, 20 in the tailored behavioural medicine treatment group and 23 in the exercise-based physiotherapy group. The groups did not differ in terms of the change in the scores for the primary outcome ( p=0.17) of pain-related disability between the experimental group (median: 2.5, Q1-Q3: -2.5-14.25), and the control group (median: 0, Q1-Q3: -5-6). Further, there were also no significant differences found for the secondary outcomes except for sickness-related absence, where the exercise-based physiotherapy group had more days of sickness-related absence three months before treatment ( p= 0.02), and at the 10-year follow-up ( p=0.03).
The beneficial effects favouring tailored behavioural medicine treatment that observed post-treatment and at the two-year follow-up were not maintained 10 years after treatment.
研究在基层医疗物理治疗环境中针对亚急性和持续性疼痛患者的两种干预措施的长期效果。
一项双臂随机对照试验的10年随访,最初纳入97名参与者。
在物理治疗背景下应用的定制行为医学治疗(试验组)和基于运动的物理治疗(对照组)。
与疼痛相关的残疾是主要结局。最大疼痛强度、疼痛控制、运动恐惧、因病缺勤(登记数据)以及应对未来疼痛问题的感知益处和信心是次要结局。
43名(44%)参与者回复了随访调查,定制行为医学治疗组20名,基于运动的物理治疗组23名。试验组(中位数:2.5,四分位间距:-2.5至14.25)和对照组(中位数:0,四分位间距:-5至6)在主要结局即与疼痛相关的残疾评分变化方面无差异(p = 0.17)。此外,除因病缺勤外,次要结局也未发现显著差异,在治疗前三个月(p = 0.02)以及10年随访时(p = 0.03),基于运动的物理治疗组因病缺勤天数更多。
治疗后及两年随访时观察到的有利于定制行为医学治疗的有益效果在治疗10年后未得到维持。