Morton Sarah U, Smith Vincent C
Harvard Neonatal-Perinatal Fellowship Program, Boston Children's Hospital Boston, Boston, Massachusetts, USA.
Department of Neonatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Arch Dis Child Fetal Neonatal Ed. 2016 Jul;101(4):F352-6. doi: 10.1136/archdischild-2015-310228. Epub 2016 Mar 22.
Apnoea of prematurity (AOP) affects almost all infants born at <28 weeks gestation or with birth weight <1000 g. When untreated, AOP may be associated with negative outcomes. Because of these negative outcomes, effective treatment for AOP is an important part of optimising care of preterm infants. Standard treatment usually involves xanthine therapy and respiratory support. Cutting-edge work with stochastic vibrotactile stimulation and new pharmaceutical agents continues to expand therapeutic options. In this article, we review the pathophysiology of AOP, associated conditions and treatment options.
早产儿呼吸暂停（AOP）几乎影响所有孕周<28周或出生体重<1000克的婴儿。未经治疗时，AOP可能会导致不良后果。由于这些不良后果，AOP的有效治疗是优化早产儿护理的重要组成部分。标准治疗通常包括黄嘌呤治疗和呼吸支持。随机振动触觉刺激和新型药物的前沿研究不断拓展治疗选择。在本文中，我们综述了AOP的病理生理学、相关情况及治疗选择。
