Organisch-Chemisches Institut, Westfälische Wilhelms-Universität Münster, Corrensstrasse 40, 48149, Münster, Germany.
Angew Chem Int Ed Engl. 2016 Apr 25;55(18):5577-81. doi: 10.1002/anie.201601003. Epub 2016 Mar 24.
A facile route toward the synthesis of isoquinolin-3-ones through a cooperative B(C6 F5 )3 - and Cp*Co(III) -catalyzed C-H bond activation of imines with diazo compounds is presented. The inclusion of a catalytic amount of B(C6 F5 )3 results in a highly efficient reaction, thus enabling unstable NH imines to serve as substrates.
通过协同 B(C6 F5 )3 和 Cp*Co(III) 催化的亚胺与重氮化合物的 C-H 键活化，提出了一种合成异喹啉-3-酮的简便途径。加入催化量的 B(C6 F5 )3 可实现高效反应，从而使不稳定的 NH 亚胺能够作为底物。
