Yuasa Yuki, Kawamura Shinji, Shiinoki Takehiro, Uehara Takuya, Koike Masahiro, Kanzaki Ryuji, Hanazawa Hideki, Takahashi Shotaro, Shibuya Keiko
Department of Radiological Technology, Yamaguchi University Hospital, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan.
Department of Therapeutic Radiology, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan.
Radiol Phys Technol. 2016 Jul;9(2):227-32. doi: 10.1007/s12194-016-0353-6. Epub 2016 Mar 24.
In high-precision radiotherapy, absolute and relative doses are evaluated for patient-specific intensity-modulated radiation therapy (IMRT) quality assurance (QA). In our institution, we use GAFCHROMIC EBT3 (EBT3) for relative dose evaluation in IMRT QA. We usually use two directional film configurations, which are in the axial and sagittal planes. The QA in our institution shows some differences between the gamma pass rates in the axial and sagittal directions. The purpose of this study was to evaluate the incident directional dependence of EBT3 by using the percent depth dose (PDD) and the off-center ratio (OCR) between EBT3 films positioned perpendicular to the beam axis and along the beam axis. Furthermore, we compared the PDD in EBT3 films positioned perpendicular to the beam axis and the PDD by using an ionization chamber. In addition, PDDs in water phantoms with and without EBT3 films were calculated by Monte Carlo simulation. The results showed that the PDD in EBT3 films positioned perpendicular to the beam axis increased with the depth from the phantom surface. Monte Carlo simulation showed the same trend as did the film measurements. The OCR results were slightly different at dose levels below 20 %. The OCR in EBT3 films positioned along the beam axis was higher than that perpendicular to the beam axis. Thus, we conclude that EBT3 film has incident directional dependence. In IMRT QA, the gamma analysis results may be affected by the incident directional dependence of EBT3 film.
在高精度放射治疗中,针对患者特异性调强放射治疗(IMRT)质量保证(QA)评估绝对剂量和相对剂量。在我们机构,我们使用GAFCHROMIC EBT3(EBT3)进行IMRT QA中的相对剂量评估。我们通常使用两种方向的胶片配置,分别位于轴向和矢状面。我们机构的QA显示轴向和矢状方向的伽马通过率存在一些差异。本研究的目的是通过使用百分深度剂量(PDD)以及垂直于射束轴和平行于射束轴放置的EBT3胶片之间的离轴比(OCR)来评估EBT3的入射方向依赖性。此外,我们比较了垂直于射束轴放置的EBT3胶片中的PDD和使用电离室测得的PDD。另外,通过蒙特卡罗模拟计算了有水模体和无水模体时的PDD。结果表明,垂直于射束轴放置的EBT3胶片中的PDD随着距模体表面深度的增加而增加。蒙特卡罗模拟显示出与胶片测量相同趋势。在剂量水平低于20%时,OCR结果略有不同。平行于射束轴放置的EBT3胶片中的OCR高于垂直于射束轴放置的胶片。因此,我们得出结论,EBT3胶片具有入射方向依赖性。在IMRT QA中,伽马分析结果可能会受到EBT3胶片入射方向依赖性的影响。