Department of Chemistry and Pharmacy, Food Chemistry, Emil Fischer Center, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) , Schuhstraße 19, 91052 Erlangen, Germany.
Biothermodynamics, TUM School of Life Sciences Weihenstephan, Technische Universität München , Gregor-Mendel Straße 4, 85354 Freising, Germany.
J Nat Prod. 2016 Apr 22;79(4):1160-4. doi: 10.1021/acs.jnatprod.5b00836. Epub 2016 Mar 24.
In a previous study, two highly potent yet unidentified odorants were detected that were present at trace levels in the volatile fraction of Boswellia sacra gum resin. These two compounds were isolated semipreparatively from the volatile oil by a sensory-guided fractionation process involving microscale bulb-to-bulb distillation, countercurrent chromatography, and preparative gas chromatography. In this manner, the two oxygenated sesquiterpenes could be identified as rotundone (1) and mustakone (2). Compound 2 is described for the first time as a potent odorant with a very low odor threshold.
在之前的一项研究中，检测到两种在乳香树脂挥发油痕量存在的高活性但未鉴定的气味物质。这两种化合物通过一种感官导向的分馏过程，包括微尺度球对球蒸馏、逆流色谱和制备气相色谱，从挥发油中半制备分离出来。通过这种方式，可以将这两种含氧倍半萜鉴定为罗酮（1）和 Mustakone（2）。2 号化合物首次被描述为一种具有非常低气味阈值的强气味物质。
