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[单剂量甲苯咪唑用于社区化疗控制活动中治疗鞭虫和美洲钩虫]

[Single dose mebendazole for the treatment of Trichuris trichiura and Necator americanus in chemotherapeutic control campaigns in the communities].

作者信息

Núñez Fernández F, Sanjurjo González E S, Finlay C M, Gálvez Oviedo D

出版信息

Rev Cubana Med Trop. 1989 Sep-Dec;41(3):371-8.

PMID:2701183
Abstract

A study of intestinal parasitism is made in "Argelia Libre" community, Isle of Youth, by means of four coproparasitologic techniques: Kato Kratz, Ritchie, Direct, and Willis. Patients with geohelminths are divided into two groups of treatment: Group A, treated with 500 mg mebendazole in single doses and group B, treated with the classical scheme of 100 mg every 12 hours for three days. Results of treatment are expressed in terms of cure rates and percentage of egg-count reduction. When comparing schemes A and B, no significant differences are found (p less than 0.05). Due to its lower cost and easier administration, the single dosage scheme is recommended for massive chemotherapy of geohelminthiasis in the community.

摘要

在青年岛的“阿尔赫利亚自由”社区,通过四种粪便寄生虫学技术(加藤厚涂片法、里氏法、直接涂片法和威利斯法)对肠道寄生虫感染情况进行了研究。感染土源性蠕虫的患者被分为两组进行治疗:A组单次服用500毫克甲苯达唑,B组按照经典方案每12小时服用100毫克,共服用三天。治疗结果以治愈率和虫卵计数减少百分比表示。比较A组和B组方案时,未发现显著差异(p小于0.05)。由于单剂量方案成本较低且给药更简便,因此推荐将其用于社区中土源性蠕虫病的大规模化疗。

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Rev Cubana Med Trop. 1989 Sep-Dec;41(3):371-8.
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