Ramírez Fernández E, Miquet Romero L, Finlay C
Instituto de Medicina Tropical Pedro Kourí.
Rev Cubana Med Trop. 1992;44(1):21-4.
People infected by Trichuris trichiura were selected in a community by the Kato-Katz technique. The study included a universe of 376 persons, male and female, positive and asymptomatic, monoparasitic and multiparasitic. They were divided in treatment groups with not less than 50 people. Monoparasitic patients were treated with 500, 400 and 300 mg of mebendazole, and multiparasitic patients with 500 and 400 mg of mebendazole. In all the cases the drug was used in single doses and its administration was supervised by the physician. Therapeutical response in monoparasitic and multiparasitic patients is shown. It is suggested to use mebendazole single doses of 300 mg in monoparasitic and of 400 mg in multiparasitic patients with an intensiveness of less than 5,000 h/g, as an alternative for treating asymptomatic populations with T. trichiura.
通过加藤厚涂片法在一个社区中挑选出感染毛首鞭形线虫的人。该研究纳入了376名男女患者，包括阳性和无症状、单寄生和多寄生的各类人群。他们被分成每组不少于50人的治疗组。单寄生患者分别接受500毫克、400毫克和300毫克甲苯达唑治疗，多寄生患者接受500毫克和400毫克甲苯达唑治疗。在所有病例中，药物均采用单次给药，且给药过程由医生监督。展示了单寄生和多寄生患者的治疗反应。建议对于每克虫卵计数强度小于5000个、感染毛首鞭形线虫的无症状人群，单寄生患者使用300毫克甲苯达唑单次给药，多寄生患者使用400毫克甲苯达唑单次给药，以此作为一种治疗选择。
