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四肽重复蛋白在光合机构生物发生中的作用。

Roles of Tetratricopeptide Repeat Proteins in Biogenesis of the Photosynthetic Apparatus.

作者信息

Bohne A-V, Schwenkert S, Grimm B, Nickelsen J

机构信息

Molecular Plant Sciences, Ludwig-Maximilians-University, Munich, Germany.

Botany, Ludwig-Maximilians-University, Munich, Germany.

出版信息

Int Rev Cell Mol Biol. 2016;324:187-227. doi: 10.1016/bs.ircmb.2016.01.005. Epub 2016 Feb 22.

Abstract

Biosynthesis of the photosynthetic apparatus is a complex operation, which includes the concerted synthesis and assembly of lipids, pigments and metal cofactors, and dozens of proteins. Research conducted in recent years has shown that these processes, as well as the stabilization and repair of this molecular machinery, are facilitated by transiently acting regulatory proteins, many of which belong to the superfamily of helical repeat proteins. Here, we focus on one of its families in photoautotrophic model organisms, the tetratricopeptide repeat (TPR) proteins, which participate in almost all of these steps and are crucial for biogenesis of the thylakoid membrane.

摘要

光合机构的生物合成是一个复杂的过程,包括脂质、色素和金属辅因子以及数十种蛋白质的协同合成与组装。近年来的研究表明,这些过程以及该分子机器的稳定和修复,都由瞬时作用的调节蛋白所促进,其中许多调节蛋白属于螺旋重复蛋白超家族。在这里,我们聚焦于光合自养模式生物中的一个家族,即四肽重复(TPR)蛋白,它们几乎参与了所有这些步骤,并且对于类囊体膜的生物发生至关重要。

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