Australian Research Council Centre of Excellence in Plant Energy Biology, School of Molecular Sciences, The University of Western Australia, Crawley 6009, Australia.
Department of Molecular Plant Sciences, LMU Munich, 82152 Martinsried, Germany.
Plant Cell. 2023 May 29;35(6):1727-1751. doi: 10.1093/plcell/koad049.
Plant organellar RNA metabolism is run by a multitude of nucleus-encoded RNA-binding proteins (RBPs) that control RNA stability, processing, and degradation. In chloroplasts and mitochondria, these post-transcriptional processes are vital for the production of a small number of essential components of the photosynthetic and respiratory machinery-and consequently for organellar biogenesis and plant survival. Many organellar RBPs have been functionally assigned to individual steps in RNA maturation, often specific to selected transcripts. While the catalog of factors identified is ever-growing, our knowledge of how they achieve their functions mechanistically is far from complete. This review summarizes the current knowledge of plant organellar RNA metabolism taking an RBP-centric approach and focusing on mechanistic aspects of RBP functions and the kinetics of the processes they are involved in.
植物细胞器 RNA 代谢由大量核编码 RNA 结合蛋白（RBPs）调控，这些蛋白控制 RNA 的稳定性、加工和降解。在线粒体和叶绿体中，这些转录后过程对于光合作用和呼吸机器中少数必需成分的产生至关重要，因此对于细胞器的生物发生和植物的生存至关重要。许多细胞器 RBPs 的功能已被分配到 RNA 成熟的单个步骤中，通常特定于选定的转录本。虽然鉴定出的因子目录在不断增加，但我们对它们如何在机制上实现其功能的了解还远远不够。本综述以 RBP 为中心，从机械方面总结了植物细胞器 RNA 代谢的最新知识，并重点介绍了 RBP 功能以及它们参与的过程的动力学。
