Hallager Dennis Winge, Gehrchen Martin, Dahl Benny, Harris Jonathan A, Gudipally Manasa, Jenkins Sean, Wu Ai-Min, Bucklen Brandon S
*Department of Orthopaedic Surgery, Copenhagen University Hospital, Copenhagen, Denmark†Musculoskeletal Education and Research Center, A Division of Globus Medical, Inc., Audubon, PA‡Department of Spinal Surgery, 2nd Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Spine (Phila Pa 1976). 2016 Apr;41(7):E388-95. doi: 10.1097/BRS.0000000000001282.
In vitro cadaveric biomechanical study.
To assess effects of 4-rod reconstruction, rod material, and anterior column support on motion and surface rod strain in a pedicle subtraction osteotomy model.
Pedicle subtraction osteotomy (PSO) can correct significant sagittal deformity of the lumbar spine; however, revision rates are high. To reduce rod strain and the incidence of rod fracture, clinical use of multi-rod construction, cobalt chrome (CoCr) alloy rods, and interbody spacers adjacent to PSO has been proposed. Investigating both motion and rod strain is necessary to determine the biomechanical efficacy of these techniques.
Five specimens (T12-S1) underwent PSO at L3 with pedicle screw stabilization at L1-S1. Pedicle subtraction was adjusted to achieve a final lordosis of 70°. Flexion-extension (FE), lateral bending, and axial rotation were applied. Linear strain gauges measured surface rod strain during FE on primary and accessory rods at PSO level. Testing evaluated (1) accessory rods (4-Rod) added at PSO level versus primary rods (2-Rod); (2) Ti versus CoCr rods; and (3) lateral interbody spacers (S) inserted adjacent to PSO. One-way and three-way analysis of variance was performed (P ≤ 0.05).
All constructs significantly reduced FE and lateral bending motion relative to intact (P < 0.001). The main effect of accessory rods in reducing FE motion was significant (P = 0.021). Accessory and CoCr rods reduced relative surface strain on the primary rod, irrespective of construct (P < 0.001). CoCr 4-Rod + S provided the greatest reduction in strain (76% decrease; P = 0.003).
Accessory and CoCr rods provided greatest reduction in motion and rod strain at PSO level. Interbody devices minimally affected motion-induced strain and might act primarily to maintain disc height. Clinicians must assess whether surface strain and motion reduction minimize the incidence of rod fracture.
N/A.
体外尸体生物力学研究。
评估在椎弓根截骨术模型中,四棒重建、棒材及前柱支撑对运动和表面棒应变的影响。
椎弓根截骨术(PSO)可矫正腰椎显著的矢状面畸形;然而,翻修率较高。为降低棒应变及棒断裂的发生率,已有人提出在临床中使用多棒结构、钴铬(CoCr)合金棒以及PSO相邻节段的椎间融合器。研究运动和棒应变对于确定这些技术的生物力学疗效很有必要。
5个标本(T12-S1)在L3处进行PSO,并在L1-S1处使用椎弓根螺钉固定。调整椎弓根截骨量以达到最终70°的前凸。施加屈伸(FE)、侧方弯曲及轴向旋转。线性应变片在PSO节段的主棒和副棒上测量FE过程中的表面棒应变。测试评估(1)在PSO节段添加副棒(4棒)与主棒(2棒);(2)钛棒与CoCr棒;(3)在PSO相邻节段植入侧方椎间融合器(S)。进行单因素和三因素方差分析(P≤0.05)。
相对于完整标本,所有结构均显著降低了FE和侧方弯曲运动(P<0.001)。副棒在降低FE运动方面的主要作用显著(P=0.021)。副棒和CoCr棒降低了主棒上的相对表面应变,与结构无关(P<0.001)。CoCr 4棒+S结构的应变降低幅度最大(降低76%;P=0.003)。
副棒和CoCr棒使PSO节段的运动和棒应变降低幅度最大。椎间装置对运动诱导应变的影响最小,可能主要作用是维持椎间盘高度。临床医生必须评估表面应变和运动降低是否能使棒断裂的发生率降至最低。
无。