Bondor Cosmina I, Veresiu Ioan A, Florea Bogdan, Vinik Etta J, Vinik Aaron I, Gavan Norina A
Department of Medical Informatics and Biostatistics, Iuliu Hațieganu University of Medicine and Pharmacy, 6 Pasteur Street, 400349 Cluj-Napoca, Romania.
Department of Diabetes, Nutrition and Metabolic Diseases, Iuliu Hațieganu University of Medicine and Pharmacy, 4-6 Clinicilor Street, 400006 Cluj-Napoca, Romania.
J Diabetes Res. 2016;2016:5439521. doi: 10.1155/2016/5439521. Epub 2016 Feb 25.
This is a post hoc analysis of quality of life in diabetic neuropathy patients in a cross-sectional survey performed in 2012 in Romania, using the Norfolk QOL-DN in which 21,756 patients with self-reported diabetes were enrolled. This current analysis aims to expand research on the diabetic foot and to provide an update on the number of foot ulcers found in Romania. Of the 21,174 patients included in this analysis, 14.85% reported a history of foot ulcers and 3.60% reported an amputation. The percentage of neuropathy patients with foot ulcers increased with age; the lowest percentage was observed in the 20-29-year age group (6.62%) and the highest in the 80-89-year age group (17.68%). The highest number of amputations was reported in the 70-79-year age group (largest group). Compared to patients without foot ulcers, those with foot ulcers had significantly higher scores for total DN and all its subdomains translating to worse QOL (p < 0.001). This analysis showed a high rate of foot ulcers and amputations in Romanian diabetic patients. It underscores the need for implementation of effective screening and educational programs.
这是对2012年在罗马尼亚进行的一项横断面调查中糖尿病神经病变患者生活质量的事后分析，该调查使用了诺福克生活质量 - 糖尿病神经病变量表，共有21,756名自我报告患有糖尿病的患者参与。本次分析旨在扩展对糖尿病足的研究，并提供罗马尼亚发现的足部溃疡数量的最新情况。在纳入本次分析的21,174名患者中，14.85%报告有足部溃疡病史，3.60%报告有截肢史。患有足部溃疡的神经病变患者百分比随年龄增加；在20 - 29岁年龄组中观察到的百分比最低（6.62%），在80 - 89岁年龄组中最高（17.68%）。截肢人数最多的报告出现在70 - 79岁年龄组（人数最多的组）。与没有足部溃疡的患者相比，有足部溃疡的患者在糖尿病神经病变总量表及其所有子领域的得分显著更高，这意味着生活质量更差（p < 0.001）。该分析表明罗马尼亚糖尿病患者中足部溃疡和截肢的发生率很高。它强调了实施有效筛查和教育项目的必要性。
