Money Nicholas P
Western Program and Department of Biology, Miami University, Oxford, OH 45056, USA.
Fungal Biol. 2016 Apr;120(4):449-453. doi: 10.1016/j.funbio.2016.01.006. Epub 2016 Jan 21.
Despite the longstanding use of dried mushrooms and mushroom extracts in traditional Chinese medicine, there is no scientific evidence to support the effectiveness of these preparations in the treatment of human disease. Consumers should evaluate assertions made by companies about the miraculous properties of medicinal mushrooms very critically. The potential harm caused by these natural products is another important consideration. In a more positive vein, the presence of potent toxins and neurotropic compounds in basidiomycete fruit bodies suggests that secondary metabolites with useful pharmacological properties are widespread in these fungi. Major investment in controlled experiments and objective clinical trials is necessary to develop this natural pharmacopeia.
尽管干蘑菇和蘑菇提取物在传统中药中早已被使用，但尚无科学证据支持这些制剂对人类疾病的治疗效果。消费者应极其审慎地评估公司对药用蘑菇神奇特性所做的断言。这些天然产品可能造成的危害是另一个重要的考虑因素。从更积极的方面来看，担子菌子实体中存在强效毒素和神经otropic化合物表明，具有有用药理特性的次生代谢产物在这些真菌中广泛存在。对对照实验和客观临床试验进行大量投资对于开发这种天然药典是必要的。
