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胆固醇结晶栓塞所致肠梗阻:一例报告。

Ileus caused by cholesterol crystal embolization: A case report.

作者信息

Azuma Shunjiro, Ikenouchi Maiko, Akamatsu Takuji, Seta Takeshi, Urai Shunji, Uenoyama Yoshito, Yamashita Yukitaka

机构信息

Shunjiro Azuma, Maiko Ikenouchi, Takuji Akamatsu, Takeshi Seta, Shunji Urai, Yoshito Uenoyama, Yukitaka Yamashita, Department of Gastroenterology, Japan Red Cross Society Wakayama Medical Center, Wakayama-city, Wakayama 640-8558, Japan.

出版信息

World J Gastroenterol. 2016 Mar 28;22(12):3502-5. doi: 10.3748/wjg.v22.i12.3502.

Abstract

Cholesterol crystal embolization (CCE) is a rare systemic embolism caused by formation of cholesterol crystals from atherosclerotic plaques. CCE usually occurs during vascular manipulation, such as vascular surgery or endovascular catheter manipulation, or due to anticoagulation or thrombolytic therapy. We report a rare case of intestinal obstruction caused by spontaneous CCE. An 81-year-old man with a history of hypertension was admitted for complaints of abdominal pain, bloating, and anorexia persisting for 4 mo. An abdominal computed tomography revealed intestinal ileus. His symptoms were immediately relieved by an ileus tube insertion, and he was discharged 6 d later. However, these symptoms immediately reappeared and persisted, and partial resection of the small intestine was performed. A histopathological examination indicated that small intestine obstruction was caused by CCE. At the 12-mo follow-up, the patient showed no evidence of CCE recurrence. Thus, in cases of intestinal obstruction, CCE should also be considered.

摘要

胆固醇结晶栓塞(CCE)是一种由动脉粥样硬化斑块形成胆固醇结晶引起的罕见全身性栓塞。CCE通常发生在血管操作期间,如血管手术或血管内导管操作,或由于抗凝或溶栓治疗。我们报告一例由自发性CCE引起肠梗阻的罕见病例。一名有高血压病史的81岁男性因腹痛、腹胀和厌食持续4个月入院。腹部计算机断层扫描显示肠梗阻。插入肠梗阻导管后他的症状立即缓解,6天后出院。然而,这些症状立即再次出现并持续存在,遂进行了小肠部分切除术。组织病理学检查表明小肠梗阻是由CCE引起的。在12个月的随访中,患者没有CCE复发的迹象。因此,在肠梗阻病例中,也应考虑CCE。

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