Acevedo Andres, Benavides Julian, Chowdhury Mohsin, Lopez Mabel, Pena Laura, Montenegro Ana, Lievano Marta, Lombo Bernardo
Conn Med. 2016 Feb;80(2):85-90.
Little is known about the role of serum uric acid in cardiovascular events. We studied the prevalence of hyperuricemia and the association between uric acid level and various cardiovascular risk factors.
This cross-sectional study was based on a population of patients with hypertension who attended a hypertension clinic in a university hospital in Bogotá, Colombia. Bivariate analysis and multivariate logistic regression models were utilized to investigate the relationship between hyperuricemia and cardiovascular risk factors.
The study population included 444 patients. The overall prevalence of hyperuricemia was 28.8%. Male gender (OR 2.3), age (OR 1.03), BMI (OR 1.09), triglyceride level (OR 1.005) and low HDL (OR 0.96) were significantly associated with hyperuricemia.
Prevalence of hyperuricemia is high in patients with hypertension. Serum uric acid is significantly associated with parameters of the metabolic syndrome. Hyperuricemia should be acknowledged and monitored as a risk factor for cardiovascular disease.
关于血清尿酸在心血管事件中的作用，人们了解甚少。我们研究了高尿酸血症的患病率以及尿酸水平与各种心血管危险因素之间的关联。
这项横断面研究基于哥伦比亚波哥大一家大学医院高血压门诊的高血压患者群体。采用双变量分析和多变量逻辑回归模型来研究高尿酸血症与心血管危险因素之间的关系。
研究人群包括444名患者。高尿酸血症的总体患病率为28.8%。男性（比值比2.3）、年龄（比值比1.03）、体重指数（比值比1.09）、甘油三酯水平（比值比1.005）和低高密度脂蛋白（比值比0.96）与高尿酸血症显著相关。
高血压患者中高尿酸血症的患病率很高。血清尿酸与代谢综合征参数显著相关。高尿酸血症应作为心血管疾病的危险因素得到认识和监测。
