Senior D G, Waters K L, Cassidy M, Crucitti T, Shapiro H, Riba A L
Conn Med. 1989 Feb;53(2):67-70.
The effects of aerobic training on left ventricular diastolic filling were determined and related to the effects on maximal oxygen uptake, left ventricular systolic function, and left ventricular mass. Nine untrained healthy males with a mean age of 32 years underwent a ten-week program of bicycle training. Echocardiographic left ventricular mass, maximal oxygen uptake, radionuclide-derived left ventricular ejection fraction, and average left ventricular filling rate were obtained before and after training. Training resulted in significant increases in maximal oxygen uptake (from 30 +/- 6 (mean +/- S.D.) to 40 +/- 7 ml/kg/min, p less than 0.001) and average left ventricular filling rate (from 2.04 +/- 0.36 to 2.22 +/- 0.31 end-diastolic volumes/sec, p less than 0.05), but no changes in heart rate, systolic blood pressure, left ventricular ejection fraction, or left ventricular mass. These data indicate that short-term high-intensity aerobic training enhances average left ventricular diastolic filling independent of any change in left ventricular geometry, systolic function, heart rate, or blood pressure.
研究了有氧训练对左心室舒张期充盈的影响，并将其与对最大摄氧量、左心室收缩功能和左心室质量的影响相关联。九名平均年龄为32岁的未经训练的健康男性接受了为期十周的自行车训练计划。在训练前后分别测量了超声心动图左心室质量、最大摄氧量、放射性核素衍生的左心室射血分数和平均左心室充盈率。训练导致最大摄氧量显著增加（从30±6（平均值±标准差）增至40±7毫升/千克/分钟，p<0.001）以及平均左心室充盈率显著增加（从2.04±0.36增至2.22±0.31舒张末期容积/秒，p<0.05），但心率、收缩压、左心室射血分数或左心室质量无变化。这些数据表明，短期高强度有氧训练可增强平均左心室舒张期充盈，且与左心室几何形状、收缩功能、心率或血压的任何变化无关。
